30 articles in this issue
Cijun Shuai, Tingting Liu, Chengde Gao, Pei Feng and Shuping Peng
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Yang Yao, Zhenxing Shi and Guixing Ren
The water-extractable (QWP) and the alkali-extractable (QAP) polysaccharides from quinoa (named QWP and QAP, respectively) and their four polysaccharide sub-fractions (QWP-1, QWP-2, QAP-1 and QAP-2), were isolated and purified by anion-exchange and gel fi... see more
Hsin-Chia Kung, Øystein Evensen, Jiann-Ruey Hong, Chia-Yu Kuo, Chun-Hsi Tso, Fang-Huar Ngou, Ming-Wei Lu and Jen-Leih Wu
The phosphatidylserine receptor (PSR) recognizes a surface marker on apoptotic cells and initiates engulfment. This receptor is important for effective apoptotic cell clearance and maintains normal tissue homeostasis and regulation of the immune response.... see more
Wei Li, Liang Wan, Ling-Yun Zhai and Jane Wang
Mengqiang Yu, Yugang Jiang, Qingliang Feng, Yi'an Ouyang and Jie Gan
Maria Del Pilar Rodríguez-Torres, Luis Armando Díaz-Torres and Sergio Romero-Servin
Reactive and pharmaceutical-grade heparins were used as biologically compatible reducing and stabilizing agents to photochemically synthesize colloidal gold nanoparticles. Aggregates and anisotropic shapes were obtained photochemically under UV black-ligh... see more
Ming Li, Kequan Guo and Susumu Ikehara
Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic cha... see more
Victoria P. A. Johnstone and Livia C. Hool
Elizabeth I. Opara and Magali Chohan
Herbs and spices have been used for both culinary and medicinal purposes for centuries. Over the last decade, research into their role as contributors of dietary polyphenols, known to possess a number of properties associated with reducing the risk of dev... see more
Lan Wang, Jinyu Wei, Ying Zou, Keyao Xu, Yuejin Wang, Lu Cui and Yan Xu
Jiao Yin, Shuang Yang, Kebin Li, Wei Guo and Yazhong Cao
Chunqiong Huang, Guodao Liu, Changjun Bai and Wenqiang Wang
Fei Shi, Wenbao Yu and Xia Wang
miRNAs are small noncoding RNAs capable of regulating gene expression at the post-transcriptional level. A growing body of evidence demonstrated that let-7 family of miRNAs, as one of the highly conserved miRNAs, plays an important role in cell differenti... see more
Claudia M. Berlanga-Reyes, Elizabeth Carvajal-Millan, Kevin B. Hicks, Madhav P. Yadav, Agustín Rascón-Chu, Jaime Lizardi-Mendoza, Alma R. Toledo-Guillén and Alma R. Islas-Rubio
Wheat bran arabinoxylan (WBAX) gels entrapping standard model proteins at different mass ratios were formed. The entrapment of protein affected the gel elasticity and viscosity values, which decreased from 177 to 138 Pa. The presence of protein did not mo... see more
Francesca Rizzello, Angelo De Paolis, Miriana Durante, Federica Blando, Giovanni Mita and Sofia Caretto
Bashar Ibrahim and Richard Henze
To guarantee genomic integrity and viability, the cell must ensure proper distribution of the replicated chromosomes among the two daughter cells in mitosis. The mitotic spindle assembly checkpoint (SAC) is a central regulatory mechanism to achieve this g... see more
Lucía Calatrava-Ferreras, Rafael Gonzalo-Gobernado, Diana Reimers, Antonio S. Herranz, Adriano Jiménez-Escrig, Juan José Díaz-Gil, María José Casarejos, María Teresa Montero-Vega and Eulalia Bazán
Michael Römer, Linus Backert, Johannes Eichner and Andreas Zell
We present a new tool for hepatocarcinogenicity evaluation of drug candidates in rodents. ToxDBScan is a web tool offering quick and easy similarity screening of new drug candidates against two large-scale public databases, which contain expression profil... see more
Cheng-Kuei Chang, Willy Chou, Hung-Jung Lin, Yi-Ching Huang, Ling-Yu Tang, Mao-Tsun Lin and Ching-Ping Chang
The heat shock protein 72 (HSP 72) is a universal marker of stress protein whose expression can be induced by physical exercise. Here we report that, in a localized model of spinal cord injury (SCI), exercised rats (given pre-SCI exercise) had significant... see more
Anna A. Brozyna, Cezary Jochymski, Zorica Janjetovic, Wojciech Józwicki, Robert C. Tuckey and Andrzej T. Slominski
The major role of 24-hydroxylase (CYP24A1) is to maintain 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) homeostasis. Recently, it has been discovered that CYP24A1 also catalyses the hydroxylation of 20(OH)D3, producing dihydroxy-derivatives that show very effect... see more
Yanlan Yao, Jinming Li and Lunan Wang
Jun Zheng and Lars Rehmann
Bioconversion of lignocellulosic biomass to bioethanol has shown environmental, economic and energetic advantages in comparison to bioethanol produced from sugar or starch. However, the pretreatment process for increasing the enzymatic accessibility and i... see more
Carolina Simó, Clara Ibáez, Alberto Valdés, Alejandro Cifuentes and Virginia García-Cañas
Metabolomic-based approaches are increasingly applied to analyse genetically modified organisms (GMOs) making it possible to obtain broader and deeper information on the composition of GMOs compared to that obtained from traditional analytical approaches.... see more
Seoungwoo Shin, Hyunwoo Kum, Dehun Ryu, Minkyung Kim, Eunsun Jung and Deokhoon Park
The phenolic compound phloretin is a prominent member of the chemical class of dihydrochalcones. Phloretin is specifically found in apple and apple juice and known for its biological properties. We were particularly interested in its potential dermo-cosme... see more
Liming Yang, Tingbo Jiang, Jake C. Fountain, Brian T. Scully, Robert D. Lee, Robert C. Kemerait, Sixue Chen and Baozhu Guo
Drought stress is a major factor that contributes to disease susceptibility and yield loss in agricultural crops. To identify drought responsive proteins and explore metabolic pathways involved in maize tolerance to drought stress, two maize lines (B73 an... see more
Tan Li and Guanyu Wang
The PI3K/Akt/mTOR pathway plays an essential role in a wide range of biological functions, including metabolism, macromolecular synthesis, cell growth, proliferation and survival. Its versatility, however, makes it a conspicuous target of many pathogens; ... see more
Young Woo Kim, Seung-Hoon Baek, Sang-Han Lee, Tae-Ho Kim and Shin-Yoon Kim
Multinucleated osteoclasts differentiate from hematopoietic progenitors of the monocyte/macrophage lineage. Because of its pivotal role in bone resorption, regulation of osteoclast differentiation is a potential therapeutic approach to the treatment of er... see more
Magda Dudek, Jessica Adams, Martin Swain, Matthew Hegarty, Sharon Huws and Joe Gallagher
Hee Jeong Kong, Ju Lan Kim, Ji Young Moon, Woo-Jin Kim, Hyung Soo Kim, Jung Youn Park, Hyun Kook Cho and Cheul Min An
Natasja Stæhr Gudmann, Jianxia Wang, Sabine Hoielt, Pingping Chen, Anne Sofie Siebuhr, Yi He, Thorbjørn G. Christiansen, Morten Asser Karsdal and Anne Christine Bay-Jensen