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ISSN: 1422-0067    frecuency : 4   format : Electrónica

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Volume 16 Number 12 Part December Year 2015

30 articles in this issue 

Ramón Cacabelos and Clara Torrellas

Epigenetic variability (DNA methylation/demethylation, histone modifications, microRNA regulation) is common in physiological and pathological conditions. Epigenetic alterations are present in different tissues along the aging process and in neurodegenera... see more

 

Amber N. Mull, Ashwini Zolekar and Yu-Chieh Wang

Melanocytes in the skin play an indispensable role in the pigmentation of skin and its appendages. It is well known that the embryonic origin of melanocytes is neural crest cells. In adult skin, functional melanocytes are continuously repopulated by the d... see more

 

Shahla Shojaei, Saeid Ghavami, Mohammad Reza Panjehshahin and Ali Akbar Owji

We aimed to compare the effects of oral ethanol (Eth) alone or combined with the phytoestrogen resveratrol (Rsv) on the expression of various brain-derived neurotrophic factor (BDNF) transcripts and the encoded protein pro-BDNF in the hippocampus of pregn... see more

 

Ercan Cacan, Alexander M. Spring, Anita Kumari, Susanna F. Greer and Charlie Garnett-Benson

Sub-lethal doses of radiation can modulate gene expression, making tumor cells more susceptible to T-cell-mediated immune attack. Proteasome inhibitors demonstrate broad anti-tumor activity in clinical and pre-clinical cancer models. Here, we use a combin... see more

 

Shunfang Wang and Shuhui Liu

An effective representation of a protein sequence plays a crucial role in protein sub-nuclear localization. The existing representations, such as dipeptide composition (DipC), pseudo-amino acid composition (PseAAC) and position specific scoring matrix (PS... see more

 

Mark L. Richter and International Journal of Molecular Sciences Editorial Office

We have been made aware that the figures and experimental data reported in the title paper [1] are duplicated in another publication by P. Bergeron [2]. [...]

 

Yuichi Tsuchiya, Osamu Nakabayashi and Hiroyasu Nakano

cFLIP (cellular FLICE-like inhibitory protein) is structurally related to caspase-8 but lacks proteolytic activity due to multiple amino acid substitutions of catalytically important residues. cFLIP protein is evolutionarily conserved and expressed as thr... see more

 

Steffen Sass, Adriana Pitea, Kristian Unger, Julia Hess, Nikola S. Mueller and Fabian J. Theis

MicroRNAs represent ~22 nt long endogenous small RNA molecules that have been experimentally shown to regulate gene expression post-transcriptionally. One main interest in miRNA research is the investigation of their functional roles, which can typically ... see more

 

Bishal Gole Tamang and Takeshi Fukao

Plants require water for growth and development, but excessive water negatively affects their productivity and viability. Flash floods occasionally result in complete submergence of plants in agricultural and natural ecosystems. When immersed in water, pl... see more

 

Yasunori Oda, Nobuhisa Kanahara and Masaomi Iyo

Although the dopamine D2 receptor (DRD2) has been a main target of antipsychotic pharmacotherapy for the treatment of schizophrenia, the standard treatment does not offer sufficient relief of symptoms to 20%–30% of patients suffering from this disorder. M... see more

 

Xuxiao Wang and Wolfgang Schrader

A heavy crude oil has been treated with deuterated alkylating reagents (CD3I and C2D5I) and directly analyzed without any prior fractionation and chromatographic separation by high-field Orbitrap Fourier Transform Mass Spectrometry (FTMS) and Fourier Tran... see more

 

Ki-Jong Rhee, Jong In Lee and Young Woo Eom

Mesenchymal stem cells (MSCs) can exhibit a marked tropism towards site of tumors. Many studies have reported that tumor progression and metastasis increase by MSCs. In contrast, other studies have shown that MSCs suppress growth of tumors. MSCs contribut... see more