30 articles in this issue
Jieun Shin, Jong-Eun Kim, Kum-Ju Pak, Jung Il Kang, Tae-Seok Kim, Sang-Yoon Lee, Ik-Hyun Yeo, Jung Han Yoon Park, Jong Hun Kim, Nam Joo Kang and Ki Won Lee
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Mi Young Ahn, Ban Ji Kim, Ha Jeong Kim, Hyung Joo Yoon, Sang Duck Jee, Jae Sam Hwang and Kun-Koo Park
Giuseppe Morgia, Antonio Micali, Mariagrazia Rinaldi, Natasha Irrera, Herbert Marini, Domenico Puzzolo, Antonina Pisani, Salvatore Privitera, Giorgio I. Russo, Sebastiano Cimino, Antonio Ieni, Vincenzo Trichilo, Domenica Altavilla, Francesco Squadrito and Letteria Minutoli
Patrick Peschl, Melanie Ramberger, Romana Höftberger, Karin Jöhrer, Matthias Baumann, Kevin Rostásy and Markus Reindl
Acute disseminated encephalomyelitis (ADEM) is a rare autoimmune-mediated demyelinating disease affecting mainly children and young adults. Differentiation to multiple sclerosis is not always possible, due to overlapping clinical symptoms and recurrent an... see more
Zaneta Król, Krzysztof Marycz, Dominika Kulig, Monika Maredziak and Andrzej Jarmoluk
Pawel Sulima, Jerzy A. Przyborowski, Anna Kuszewska, Dariusz Zaluski, Malgorzata Jedryczka and Witold Irzykowski
Kohji Ohki, Hiromichi Wakui, Kengo Azushima, Kazushi Uneda, Sona Haku, Ryu Kobayashi, Kotaro Haruhara, Sho Kinguchi, Miyuki Matsuda, Masato Ohsawa, Akinobu Maeda, Shintaro Minegishi, Tomoaki Ishigami, Yoshiyuki Toya, Akio Yamashita, Satoshi Umemura and Kouichi Tamura
Dora Werling, William A. Banks, Therese S. Salameh, Timea Kvarik, Laszlo Akos Kovacs, Alexandra Vaczy, Edina Szabo, Flora Mayer, Rita Varga, Andrea Tamas, Gabor Toth, Zsolt Biro, Tamas Atlasz and Dora Reglodi
The neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP) has two active forms, PACAP1-27 and PACAP1-38. Among the well-established actions are PACAP’s neurotrophic and neuroprotective effects, which have also been proven in models of di... see more
Santosh Lamichhane, Tonking Bastola, Ramesh Pariyar, Eun-Sol Lee, Ho-Sub Lee, Dae Ho Lee and Jungwon Seo
Juan Zou, Jason Y. Jiang and Jenny J. Yang
Metabotropic glutamate receptors (mGluRs) associated with the slow phase of the glutamatergic signaling pathway in neurons of the central nervous system have gained importance as drug targets for chronic neurodegenerative diseases. While extracellular Ca2... see more
Ji Hoon Park, Bo Keun Lee, Seung Hun Park, Mal Geum Kim, Jin Woo Lee, Hye Yun Lee, Hai Bang Lee, Jae Ho Kim and Moon Suk Kim
Alejandro Chamizo-Ampudia, Aurora Galvan, Emilio Fernandez and Angel Llamas
Yazmín Espinosa, Camila San Martín, Alejandro A. Torres, Mauricio J. Farfán, Juan P. Torres, Vasanthi Avadhanula, Pedro A. Piedra and Lorena I. Tapia
Patricia Reboredo-Rodríguez, María Figueiredo-González, Carmen González-Barreiro, Jesús Simal-Gándara, María Desamparados Salvador, Beatriz Cancho-Grande and Giuseppe Fregapane
Virgin olive oil, the main fat of the Mediterranean diet, is per se considered as a functional food—as stated by the European Food Safety Authority (EFSA)—due to its content in healthy compounds. The daily intake of endogenous bioactive phenolics from vir... see more
John C. Chang and Madappa Kundranda
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease for a multitude of reasons including very late diagnosis. This in part is due to the lack of understanding of the biological behavior of PDAC and the ineffective screening for this disease... see more
Takahisa Kouwaki, Masaaki Okamoto, Hirotake Tsukamoto, Yoshimi Fukushima and Hiroyuki Oshiumi
The innate immune system plays a crucial role in controlling viral infection. Pattern recognition receptors (PRRs), such as Toll-like receptors and RIG-I-like receptors, sense viral components called pathogen-associated molecular patterns (PAMPs) and trig... see more
Alexandria Hughes, Alexandra E. Oxford, Ken Tawara, Cheryl L. Jorcyk and Julia Thom Oxford
Chondrocytes of the growth plate undergo apoptosis during the process of endochondral ossification, as well as during the progression of osteoarthritis. Although the regulation of this process is not completely understood, alterations in the precisely orc... see more
Ravindra G. Heendeniya and Peiqiang Yu
Chiu-Yen Chung, Martin Hsiu-Chu Lin, I-Neng Lee, Tsong-Hai Lee, Ming-Hsueh Lee and Jen-Tsung Yang
Marta González-Arto, David Aguilar, Elena Gaspar-Torrubia, Margarita Gallego, Melissa Carvajal-Serna, Luis V. Herrera-Marcos, Edith Serrano-Blesa, Thais Rose dos Santos Hamilton, Rosaura Pérez-Pé, Teresa Muiño-Blanco, José A. Cebrián-Pérez and Adriana Casao
Michael T. Eadon, Ronald J. Hause, Amy L. Stark, Ying-Hua Cheng, Heather E. Wheeler, Kimberly S. Burgess, Eric A. Benson, Patrick N. Cunningham, Robert L. Bacallao, Pierre C. Dagher, Todd C. Skaar and M. Eileen Dolan
Teresa Papalia, Davide Barreca and Maria Rosaria Panuccio
Juliana Magdalon, Sandra M. Sánchez-Sánchez, Karina Griesi-Oliveira and Andréa L. Sertié
Whereas autism spectrum disorder (ASD) exhibits striking heterogeneity in genetics and clinical presentation, dysfunction of mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway has been identified as a molecular feature common to several ... see more
Francisco J. Estades-Rubio, Alvaro Reyes-Martín, Victor Morales-Marcos, Mercedes García-Piriz, Juan J. García-Vera, Macarena Perán, Juan A. Marchal and Elvira Montañez-Heredia
Given the wide difference in price per vial between various presentations of hyaluronic acid, this study seeks to compare the effectiveness and treatment cost of stabilized hyaluronic acid (NASHA) in a single injection with standard preparations of hyalur... see more
Thomas Schmoch, Florian Uhle, Benedikt H. Siegler, Thomas Fleming, Jakob Morgenstern, Peter P. Nawroth, Markus A. Weigand and Thorsten Brenner
Sepsis remains one of the leading causes of death in intensive care units. Although sepsis is caused by a viral, fungal or bacterial infection, it is the dysregulated generalized host response that ultimately leads to severe dysfunction of multiple organs... see more
Thazin Nwe Aung, Zhipeng Qu, R. Daniel Kortschak and David L. Adelson
Many approaches to cancer management are often ineffective due to adverse reactions, drug resistance, or inadequate target specificity of single anti-cancer agents. In contrast, a combinatorial approach with the application of two or more anti-cancer agen... see more
Nesli Avgan, Heidi G. Sutherland, Lauren K. Spriggens, Chieh Yu, Omar Ibrahim, Claire Bellis, Larisa M. Haupt, David H. K. Shum and Lyn R. Griffiths
Tânia Costa Silva, Paula Branquinho De Andrade, Fátima Paiva-Martins, Patrícia Valentão and David Micael Pereira
Joshua B. Lewis, Kelsey M. Hirschi, Juan A. Arroyo, Benjamin T. Bikman, David L. Kooyman and Paul R. Reynolds
Approximately 1 billion people smoke worldwide, and the burden placed on society by primary and secondhand smokers is expected to increase. Smoking is the leading risk factor for myriad health complications stemming from diverse pathogenic programs. First... see more
Henry Barron, Sina Hafizi, Ana C. Andreazza and Romina Mizrahi