30 articles in this issue
Hai-Long Zhao, Zhong-Kui Xia, Fa-Zhan Zhang, Yuan-Nong Ye and Feng-Biao Guo
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HyeonSeok Shin and Byung-Kwan Cho
Sequence–function relationship in a protein is commonly determined by the three-dimensional protein structure followed by various biochemical experiments. However, with the explosive increase in the number of genome sequences, facilitated by recent advanc... see more
Natsuko I. Kobayashi and Keitaro Tanoi
Daniela Hirschburger, Manuel Müller, Ralf T. Voegele and Tobias Link
Pensée Wu, Caroline Van den Berg, Zarko Alfirevic, Shaughn O’Brien, Maria Röthlisberger, Philip Newton Baker, Louise C. Kenny, Karolina Kublickiene and Johannes J. Duvekot
Pre-eclampsia (PE) complicates 2%–8% of all pregnancies and is an important cause of perinatal morbidity and mortality worldwide. In order to reduce these complications and to develop possible treatment modalities, it is important to identify women at ris... see more
Francisco López-Muñoz, Javier Sanz-Fuentenebro, Gabriel Rubio, Pilar García-García and Cecilio Álamo
Hongrui Guo, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Bangyuan Wu, Kejie Chen and Jie Deng
Exposure of people and animals to environments highly polluted with nickel (Ni) can cause pathologic effects. Ni compounds can induce apoptosis, but the mechanism and the pathway of Ni compounds-induced apoptosis are unclear. We evaluated the alterations ... see more
Sally Temraz, Deborah Mukherji and Ali Shamseddine
Colorectal cancer (CRC) is a heterogeneous disease with multiple underlying causative genetic mutations. Genetic mutations in the phosphatidylinositol-3 kinase (PI3K) and the mitogen activated protein kinase (MAPK) pathways are frequently implicated in CR... see more
Huiyan Guo, Yucheng Wang, Huizi Liu, Ping Hu, Yuanyuan Jia, Chunrui Zhang, Yanmin Wang, Shan Gu, Chuanping Yang and Chao Wang
Na Zhou, Yizhuang Zhang, Xuehui Zhang, Zhen Lei, Ruobi Hu, Hui Li, Yiqing Mao, Xi Wang, David M. Irwin, Gang Niu and Huanran Tan
Fanwei Dai, Zhenjiang Wang, Guoqing Luo and Cuiming Tang
Yunhui Li, Minhui Zhang, Pan Chen, Ran Liu, Geyu Liang, Lihong Yin and Yuepu Pu
Anqi Wang, Fei Liu, Shun Chen, Mingshu Wang, Renyong Jia, Dekang Zhu, Mafeng Liu, Kunfeng Sun, Ying Wu, Xiaoyue Chen and Anchun Cheng
Peiying Hao, Chaofeng Lu, Yan Ma, Lingbo Xu, Jiajun Zhu and Xiaoping Yu
Georgios A. Christou, Konstantinos A. Christou, Panagiotis Korantzopoulos, Evangelos C. Rizos, Dimitrios N. Nikas and John A. Goudevenos
Background: The main dietary source of omega-3 polyunsaturated fatty acids (n-3 PUFA) is fish, which contains eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In the present manuscript, we aimed to review the current evidence regarding the clin... see more
Yun Zhao, Zhuqi Tang, Aiguo Shen, Tao Tao, Chunhua Wan, Xiaohui Zhu, Jieru Huang, Wanlu Zhang, Nana Xia, Suxin Wang, Shiwei Cui and Dongmei Zhang
Lian Chen and Hengmin Cui
Marialuisa Polillo, Sara Galimberti, Claudia Baratè, Mario Petrini, Romano Danesi and Antonello Di Paolo
Jiaqiang Zhao, Lizhi Peng, Wenhua Zheng, Rikang Wang, Lei Zhang, Jian Yang and Heru Chen
Two amantadine (ATD)-gardenamide A (GA) ligands have been designed and synthesized. The bonding of ATD with GA through a methylene carbonyl brigde (L1) enhances the neuroprotective effect against corticosterone (CORT)-induced impairments in PC12 cells; wh... see more
Ryota Uchida, Hinako Okamoto, Naoko Ikuta, Keiji Terao and Takashi Hirota
Makoto Chikira, Chew Hee Ng and Mallayan Palaniandavar
The interaction of simple and ternary Cu(II) complexes of 1,10-phenanthrolines with DNA has been studied extensively because of their various interesting and important functions such as DNA cleavage activity, cytotoxicity towards cancer cells, and DNA bas... see more
H. Edward Wong and Inchan Kwon
Techniques to incorporate non-natural amino acids (NNAAs) have enabled biosynthesis of proteins containing new building blocks with unique structures, chemistry, and reactivity that are not found in natural amino acids. It is crucial to understand how inc... see more
Yu-Li Lo, Hsin-Pin Lee and Wei-Chen Tu
This study aims to explore the effects and mechanisms of hepcidin, a potential antimicrobial peptide from Tilapia, and epirubicin (Epi), an antineoplastic agent, on the generation of reactive oxygen species (ROS) and link the ROS levels to the reversal me... see more
Jiangnan Huang, Ruize Liu, Lijie Su, Qian Xiao and Mei Yu
The expression patterns in Meishan- and Yorkshire-derived endometrium during early (gestational day 15) and mid-gestation (gestational days 26 and 50) were investigated, respectively. Totally, 689 and 1649 annotated genes were identified to be differentia... see more
Venu Venkatarame Gowda Saralamma, Arulkumar Nagappan, Gyeong Eun Hong, Ho Jeong Lee, Silvia Yumnam, Suchismita Raha, Jeong Doo Heo, Sang Joon Lee, Won Sup Lee, Eun Hee Kim and Gon Sup Kim
Poncirin, a natural bitter flavanone glycoside abundantly present in many species of citrus fruits, has various biological benefits such as anti-oxidant, anti-microbial, anti-inflammatory and anti-cancer activities. The anti-cancer mechanism of Poncirin r... see more
Xin Zhang, Qingshan You, Xiaolei Zhang and Xiangmei Chen
Hanne K. Maehre, Ida-Johanne Jensen, Edel O. Elvevoll and Karl-Erik Eilertsen
Zhizhi Hu, Guangchang Pei, Pengge Wang, Juan Yang, Fengmin Zhu, Yujiao Guo, Meng Wang, Ying Yao, Rui Zeng, Wenhui Liao and Gang Xu
Rui-Long Wang, Christian Staehelin, Qing-Qing Xia, Yi-Juan Su and Ren-Sen Zeng
Valentina Perri, Benedetta Russo, Antonino Crinò, Riccardo Schiaffini, Ezio Giorda, Marco Cappa, Maria Manuela Rosado and Alessandra Fierabracci