30 articles in this issue
Laura Mercatali, Federico La Manna, Arwin Groenewoud, Roberto Casadei, Federica Recine, Giacomo Miserocchi, Federica Pieri, Chiara Liverani, Alberto Bongiovanni, Chiara Spadazzi, Alessandro De Vita, Gabri Van der Pluijm, Andrea Giorgini, Roberto Biagini, Dino Amadori, Toni Ibrahim and Ewa Snaar-Jagalska
Bone metastasis is a complex process that needs to be better understood in order to help clinicians prevent and treat it. Xenografts using patient-derived material (PDX) rather than cancer cell lines are a novel approach that guarantees more clinically re... see more
Ou Yun, Xin-An Zeng, Charles S. Brennan and Zhong Han
-
Shaobing Cheng, Xu Jiang, Chaofeng Ding, Chengli Du, Kwabena Gyabaah Owusu-Ansah, Xiaoyu Weng, Wendi Hu, Chuanhui Peng, Zhen Lv, Rongliang Tong, Heng Xiao, Haiyang Xie, Lin Zhou, Jian Wu and Shusen Zheng
Interleukin enhancer binding factor 2 (ILF2), a transcription factor, regulates cell growth by inhibiting the stabilization of mRNA. Currently, its role has gained recognition as a factor in the tumorigenic process. However, until now, little has been kno... see more
Matheus Aparecido Dos Santos Ramos, Luciani Gaspar De Toledo, Giovana Maria Fioramonti Calixto, Bruna Vidal Bonifácio, Marcelo Gonzaga De Freitas Araújo, Lourdes Campaner Dos Santos, Margarete Teresa Gottardo De Almeida, Marlus Chorilli and Taís Maria Bauab
Jixuan Ma, Xiuqing Cui, Yi Rong, Yun Zhou, Yanjun Guo, Min Zhou, Lili Xiao and Weihong Chen
Susana Flores, Iván Montenegro, Joan Villena, Mauricio Cuellar, Enrique Werner, Patricio Godoy and Alejandro Madrid
Anna Koziróg, Katarzyna Rajkowska, Anna Otlewska, Malgorzata Piotrowska, Alina Kunicka-Styczynska, Bogumil Brycki, Paulina Nowicka-Krawczyk, Marta Koscielniak and Beata Gutarowska
Emmanuel Vázquez-Mayorga, Ángel G. Díaz-Sánchez, Ruben K. Dagda, Carlos A. Domínguez-Solís, Raul Y. Dagda, Cynthia K. Coronado-Ramírez and Alejandro Martínez-Martínez
Adrienn Csányi, Judit Bóta, George Falkay, Robert Gáspár and Eszter Ducza
Thirteen mammalian aquaporin (AQP) water channels are known, and few of them play a role in the mammalian reproductive system. In our earlier study, the predominance of AQP5 in the late-pregnant rat uterus was proven. Our current aim was to investigate th... see more
He Zhou, Tian-Yu Ma, Rui Zhang, Qi-Zheng Xu, Fu Shen, Yan-Jie Qin, Wen Xu, Yuan Wang and Ya-Juan Li
Aixing Wang, Chao Fang and Yibao Liu
Yanwei Li, Ruiming Zhang, Likai Du, Qingzhu Zhang and Wenxing Wang
The quantum mechanics/molecular mechanics (QM/MM) method (e.g., density functional theory (DFT)/MM) is important in elucidating enzymatic mechanisms. It is indispensable to study “multiple” conformations of enzymes to get unbiased energetic and structural... see more
Nicolino Pala, Francesca Esposito, Dominga Rogolino, Mauro Carcelli, Vanna Sanna, Michele Palomba, Lieve Naesens, Angela Corona, Nicole Grandi, Enzo Tramontano and Mario Sechi
Xiaochen Qu, Zhongqiang Chen, Dongwei Fan, Chuiguo Sun and Yan Zeng
Rong-Hua Song, Qiong Wang, Qiu-Ming Yao, Xiao-Qing Shao, Ling Li, Wen Wang, Xiao-Fei An, Qian Li and Jin-An Zhang
Jiunn-Ming Sheen, Yu-Chieh Chen, Mei-Hsin Hsu, You-Lin Tain, Ying-Hsien Huang, Mao-Meng Tiao, Shih-Wen Li and Li-Tung Huang
Bile duct ligation (BDL)-treated rats display cholestasis and liver damages. The potential protective activity of melatonin in young BDL rats in terms of apoptosis, mitochondrial function, and endoplasmic reticulum (ER) homeostasis has not yet been evalua... see more
Rawana N. Alkhalili, Katja Bernfur, Tarek Dishisha, Gashaw Mamo, Jenny Schelin, Björn Canbäck, Cecilia Emanuelsson and Rajni Hatti-Kaul
Paola Savoia, Giovanni Cavaliere, Elisa Zavattaro, Federica Veronese and Paolo Fava
Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely ... see more
Xiao-Min Shen, Chong-Yu Liao, Xue-Ping Lu, Zhe Wang, Jin-Jun Wang and Wei Dou
Zhimao Mai, Hongfei Su and Si Zhang
Yi-Ning Chao, David Sun, Yen-Chun Peng and Yuh-Lin Wu
Cyclooxygenase-2 (COX-2) and interleukin-8 (IL-8) are two important inflammatory mediators in ovulation. Ghrelin may modulate inflammatory signaling via growth hormone secretagogue receptors. We investigated the role of ghrelin in KGN human ovarian granul... see more
Petr Cársky
This book, with its 2889 pages in ?ve volumes, represents an impressive piece of work written by a single author.[...]
Milena Rondón-Lagos, Victoria E. Villegas, Nelson Rangel, Magda Carolina Sánchez and Peter G. Zaphiropoulos
17ß-Estradiol (E2) plays a pivotal role in the development and progression of breast cancer. As a result, blockade of the E2 signal through either tamoxifen (TAM) or aromatase inhibitors is an important therapeutic strategy to treat or prevent estrogen re... see more
Xian Zhang, Xue Feng, Jiemeng Tao, Liyuan Ma, Yunhua Xiao, Yili Liang, Xueduan Liu and Huaqun Yin
Xi-Feng Zhang, Qi Yan, Wei Shen and Sangiliyandi Gurunathan
Cervical cancer ranks seventh overall among all types of cancer in women. Although several treatments, including radiation, surgery and chemotherapy, are available to eradicate or reduce the size of cancer, many cancers eventually relapse. Thus, it is ess... see more
Madumani Amararathna, Michael R. Johnston and H. P. Vasantha Rupasinghe
Lung cancer may be prevented by a diet rich in fruits and vegetables as they are enriched with dietary antioxidant polyphenols, such as flavonoids, proanthocyanidins, lignans, stilbenes, and phenolic acids. Dietary polyphenols exert a wide range of benefi... see more
Ming Liu, Fangling Chen, Rilei Yu, Weiyi Zhang, Mei Han, Fei Liu, Jing Wu, Xingzeng Zhao and Jinlai Miao
Vinicius C. Soeiro, Karoline R. T. Melo, Monique G. C. F. Alves, Mayara J. C. Medeiros, Maria L. P. M. Grilo, Jailma Almeida-Lima, Daniel L. Pontes, Leandro S. Costa and Hugo A. O. Rocha
Xiao Li, Jing Yang, Youbo Zhu, Yuan Liu, Xin’e Shi and Gongshe Yang
Yong-Feng Hou, Si-Hai Gao, Ping Wang, He-Mei Zhang, Li-Zhi Liu, Meng-Xuan Ye, Guang-Ming Zhou, Zeng-Li Zhang and Bing-Yan Li
Ovarian cancer is the most lethal gynecological malignancy due to its high metastatic ability. Epithelial-mesenchymal transition (EMT) is essential during both follicular rupture and epithelium regeneration. However, it may also accelerate the progression... see more