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102  Articles
1 of 11 pages  |  10  records  |  more records»
Diabetic retinopathy (DR) has been classically considered a microcirculatory disease of the retina. However, there is growing evidence to suggest that retinal neurodegeneration is also an early event in the pathogenesis of DR. Citicoline has been successf... see more

The elimination of abnormal and dysfunctional cellular constituents is an essential prerequisite for nerve cells to maintain their homeostasis and proper function. This is mainly achieved through autophagy, a process that eliminates abnormal and dysfuncti... see more

Traumatic brain injury (TBI) can result in persistent sensorimotor and cognitive deficits, which occur through a cascade of deleterious pathophysiological events over time. In this study, we investigated the hypothesis that neurodegeneration caused by TBI... see more

This report aimed to describe and review the clinical features, neuroimaging findings, and PLA2G6 mutations identified in a 34-month-old girl with regression of developmental milestones.A 34 months old girl came to Dr.Soetomo Hospital’s outpatient clinic,... see more

Alzheimer’s disease (AD) is a neurodegenerative disease. It is a growing concern, demanding the attention of families, scientists, and pharmaceutical companies due to its devastating impacts on patients. The disease is believed to be triggered by pathogen... see more

Extracts from Origanum majorana L. are used in Asia and Africa as sedatives and neurotonics. Few studies done to explore the active chemical constituents responsible for this apparent contrast. The inhibitory glycine receptors (GlyRs) are key mediators of... see more

Background: Elderly stroke survivors have been reported to be at risk of malnutrition and depression. Vitamin B-related metabolites such as methylmalonic acid and homocysteine have been implicated in depression. Objective: We conducted a study exploring t... see more

In this paper, the main epigenetic factors involved in shaping the brain’s physical structure during development will be reviewed, with special emphasis on those related to Parkinson’s disease and Alzheimer’s disease in adulthood. These factors are: prete... see more

Paper description:Pantothenate kinase-associated neurodegeneration (PKAN) is a rare autosomal recessive disorder caused by mutations in the PANK2 gene which encodes for pantothenate kinase 2. Different PANK2 mutations are detected worldwide, but all 6 Ser... see more

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