19 articles in this issue
Muhammad Imran Qadir, Zara Ahmad
Hepatic dysfunction is a major catastrophe that challenges the health concern researchers. Multiple factors such as biological, chemical and drug overdose are associated with liver disorders. Man-made pharmaceutical preparations, which are usually used fo... see more
Alshammari Fanar Hamad, Hye-Young Jeong, Jong-Hun Han, Irfan Ahmad Rather
Out of entire cascade of technologies and strategies, Northern blot assay remains the most preferential approach for immediate and accurate evaluation of expressed RNA species. However, an abundance of tRNAs species under physiological conditions compared... see more
Fahmida Hasnat, Habiba Akhter Bhuiyan, Mir Misbahuddin
High performance liquid chromatography was used to develop and validate the detection of vitamin B12 in blood plasma sample. The mobile phase consists of a mixture of 0.025% trifluroacetic acid in deionized water and 30% methanol. The mixture used was adj... see more
Xuelian Bai, Ting Zhou, Tongfei Lai, Yicong Li, Jiale Chai, Jiajun Ni, Huawei Zhang
Sixteen fungal strains isolated from the Erigeron canadensis, one of traditional Chinese medicines used to treat the pathogenic infection and dysentery, were evaluated for their antifungal activities against one human pathogen Candida albicans, and two ph... see more
Ilhem Bencherchar, Ibrahim Demirtas, Muhammed Altun, Fatih Gul, Djamel Sarri, Fadila Benayache, Samir Benayache, Ratiba Mekkiou
The prevention and treatment of the cancer using plants have attracted increasing interest. The present study was aimed to determine the phenolic compounds of Genista ferox using HPLC-TOF/MS and the anti-oxidant acti-vity associated with anti-cancer activ... see more
Renuka Saravanan, Brindha Pemaiah, Sriram Sridharan, Mahesh Narayanan, Sivakumar Ramalingam
The aim of the present study was to analyze the anti-cancer effect of Orthosiphon stamineus leaf extract on MCF-7 cells. Ethyl acetate extract of the plant was eluted and pooled into 6 fractions based on their Rf values and the fractions were tested for c... see more
Atta ur Rehman, Manal Liaqat, Rabia Asghar, Nawazish-i-Husain Syed
Phragmites karka has been reported for its anti-inflammatory and analgesic activities. Here, extracts of leaf and rhizome of the plant were individually investigated in CCl4-induced hepatofibrosis in male Wistar rats by administering CCl4 intraperito... see more
Kandasamy Sasikumar, Asit Ranjan Ghosh
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Uzma Saleem, Nauman Ali, Bashir Ahmad
The objective of current study was to evaluate the nephroprotective and nephrocurative effects of methanolic extract of Cestrum nocturnum leaves in rabbits. Gentamicin (80 mg/kg/day) was administered intramuscularly to induce nephrotoxicity. The induction... see more
Fiaz Alam, Qazi Najam us Saqib
This study evaluated Gaultheria trichophylla for its in vitro and in vivo anti-diabetic activity and its effect on biochemical parameters. The extract inhibited ?-glucosidase with IC50 = 17.5 ± 0.1 ?g/mL). The difference of body weight of the extract-trea... see more
Lei Zheng, Hao He, Xuji Shen, Yanping Sun
The aim of this study was to examine the anti-proliferation and anti-migration effect of Centipede Scolopendra extracts (CSE) on human epidermoid carcinoma cells (high-EGFR expression) A431 and elucidate the underlying signaling mechanisms. MTT and colony... see more
Yanfang Zhang, Jianxun Sun, Hui Liu, Xiaolin Zhai
The diabetic patients (n=109) with mild or moderate renal insufficiency underwent coronary intervention were randomly divided into control group and observation group. The patients in observation group were treated with injection Shenkang and alprostadil ... see more
Wajid Khan, Jehan Bakht, Bilal Muhammad Khan
The different parts of Physalis philadelphica were evaluated for the antifungal, anti-oxidant and HPLC assay. The methanol extract of leaf showed inhibitory activity against Pencillium digitatum (58% ZI), Aspergillus flavus (95% ZI) and Rhizopus oryzae (9... see more
Mubeen Arif, Furukh Jabeen, Aamer Saeed, Irfan Zia Qureshi, Nadia Mushtaq
Two new pharmacologically active series of tetrazolopyridine-acetohydrazide conjugates [9 (a-n), 10 (a-n)] were synthesized by reacting a variety of suitably substituted benzaldehydes and isomeric 2-(5-(pyridin-3/4-yl)-2H-tetrazol-2-yl)acetohydrazides (7,... see more
Venugopal Gopikrishnan, Manickkam Radhakrishnan, Raasaiyah Pazhanimurugan, Thangavel Shanmugasundaram, Ramasamy Balagurunathan
Uzma Saleem, Ejaz ul Haq, Bashir Ahmad, Mohammad Saleem
This study was planned to explore the antiulcer activity of the methanolic and n-hexane extracts of Cestrum nocturnum leaf against ethanol- and indomethacin-induced ulcer models in rats. The rats were administered orally vehicle in normal control group, m... see more
Wei Lan, Hong Ping Zhang, Ying Wang, Min Jiang, Qian Li, Dongqing An
The purpose of this study was to investigate the antihypertensive mecha-nisms of piperitenone oxide in spontaneously hypertensive rat (SHR). Compared to control SHR, piperitenone oxide reduced the systolic blood pressure and serum endothelium-1 (ET-1). Th... see more
Muhammad Farhan Bashir, Muhammad Imran Qadir
Angiogenesis performs a critical role in the embryonic growth and several pathological conditions in cancer. This study evaluated the anti-angiogenic properties of the ginger extract using CAM assay. Ginger extract was prepared by methanol. Window was mad... see more
Saiqa Ishtiaq, Muhammad Shaharyar Khan Afridi, Nawal Masood
Amaranthus graecizans subsp. silvestris, a folk medicine for the treatment of inflammation, was used to evaluate its hepatoprotective potential against rifampicin and isoniazid-induced liver damage. Wistar albino rats were divided into four groups: Group ... see more