21 articles in this issue
Muhammad Abdullah Shah, Syed Muhammad Abdullah, Muhammad Azim Khan, Gulfam Nasar, Irum Saba
Asparagus racemosus is a medical extensively used in traditional medicine for various disorders including its use in infectious. So far work has been done to identify its active constituents responsible for antiseptic folk use of this plant. In the curren... see more
Afjal Hussain Mazumder, Jayshree Das, Hemanta Kumar Gogoi, Pronobesh Chattopadhyay, Satya Bhusan Paul
Antimicrobial evaluation of methanol extract of Sarcochlamys pulcherrima leaf and its hexane, ethyl acetate, n-butanol and water fractions against 31 strains of microorganisms, using agar well, agar disc diffusion, and broth microdilution methods, reveale... see more
Polo-Ma-Abiele Hildah Ntsoelinyane, Samson Mashele
The aim of this study was to investigate antioxidant activities, antibacterial activities and a phytochemical constituent of Asparagus laricinus stem and leaf extracts. Determination of antibacterial activity of extracts was assessed by agar dilution meth... see more
Tahmina Bashar, Mir Misbahuddin, Md. Amir Hossain
This study was done to examine the role of Nigella sativa in 28 patients of palmar arsenical keratosis. Patients were randomized into two groups: Group A (n-15) receive capsules of placebo and vitamin E (200 mg) whereas Group B (n= 13) receive capsules of... see more
K. V. N. Rathnakar Reddi, Sivarathri Siva Rajesh, Kumara Narendra, Swathi Jangala, Puli Chandra Obul Reddy, Alapati Krishna Satya, Thirunavukkarasu Sivaraman, Akila Chandra Sekhar
In present study various species of Jatropha were evaluated for antidote nature induced by phospholipase A2 (PLA2) cobra venom. Although qualitative phytochemical analysis exhibited less variation across Jatropha species studied, substantial variabil... see more
Shahid Muhammad Iqbal, Aamir Mushtaq, Qaiser Jabeen
Traditional healers in Pakistan use the herb Amberboa divaricata as tonic, aperiant, deobstruent, febrifuge, antidiarrheal, antiperiodic, antipyretic, anti-cough and in skin disorders. In vitro tissue experiments were carried out on rabbit jejunum to eluc... see more
Divya S. Mohan, Mini Saraswathy, Muraleedhara Kurup Gopala Kurup
In the present study, the effect of defatted hydromethanolic extract of Padina tetrastromatica on carbohydrate metabolism and serum lipid profile were evaluated. Diabetes mellitus was induced in male Wistar rats by feeding high calorie/energy diet for two... see more
Mohamed I. Attia, Hazem A. Ghabbour, Azza S. Zakaria, Hoong-Kun Fun
Synthesis, characterization, and anti-Candida activity of ({(E)-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]amino}oxy)(4-nitrophenyl)methanone (4) are reported. Compound 4 showed anti-Candida albicans activity (MIC = 0.6862 µmol/mL) being nearly 5-fold more... see more
Sonia George, Mohammed Basheer Ramzeena, Sayee Vignesh Ram, Senthil Kumar Selvaraj, Shinu Rajan, Thengungal Kochupappy Ravi
A series of 1-phenyl-[5-substitutedphenyl)-1,3,4-thiadiazol-2-yl]-3-thiourea (3a-h) were synthesized and screened for their anti Escherichia coli potential. The characterization of the newly synthesized compounds was based upon their spectral data. The de... see more
Mani Arunkumar, Karuppaiyan Suhashini, Narayanan Mahesh, Raju Ravikumar
Development of efficient methodology for the green synthesis of silver nanoparticles using marine algae is a modern area of research in the field of phyconanotechnology. In this regard, the present study deals with green synthesis of silver nanoparticles ... see more
Tauqeer Hussain Mallhi, M. Imran Qadir, Yusra Habib Khan, Muhammad Ali
Morus nigra (Family Moraceae) is traditionally used injaundice, diabetes, hypertension, cough, fever and cancer. The current study was conducted to determine hepatoprotective activity of aqueous methanolic extract of leaves of M. nigra. Two doses of 250 m... see more
Tarali Chowdhury
With the emergence of multi-drug resistant pathogens at alarming frequency, there has been an increase interest in the development of novel drugs from natural resources. The use of higher plants and preparations made from them to treat infections is a lon... see more
Arumugam Madeswaran, Kuppusamy Asokkumar, Muthuswamy Umamaheswari, Thirumalaisamy Sivashanmugam, Varadharajan Subhadradevi, Puliyath Jagannath
The primary objective of this study was to investigate the a-amylase inhibitory activity of flavonoids using in silico docking studies. In this perspective, flavonoids like biochanin, chrysin, hesperitin, morin, tricin and vitexycarpin were selected. Acar... see more
Radhakrishnan Narayanaswamy, Lam Kok Wai, Faridah Abas, Intan Safinar Ismail
In the present study, we aimed to dock 17 different ligands of curcumin analogues with that of human neutrophil elastase. Molecular descriptors analysis using Molinspiration online tool was carried out including investigation on human neutrophil elastase ... see more
Pratap Parida, Priyadarshini Deka, Brajesh Shankar, R. N. S. Yadav
Nonstructural protein 3 (NS3) constitute protease, helicase and polymerase that are essential for dengue virus replication. The aim of the present study is to block the replication of the virus by targeting the NS3 Protein. The retrieved sequences of NS3 ... see more
Pratap Parida, Samhita Kalita, R. N. S. Yadav, Brajesh Shankar
The telomerase reverse transcriptase (TERT) sequence from Plasmodium falciparum provides valuable information for the design of specific anti-telomerase drugs. The present study deals with the interaction of pfTERT against berberine derivatives to derive ... see more
S. Q. Njabulo Lamula, A. O. Tom Ashafa
The antimicrobial potential of Dianthus basuticus extracts were investigated using 96 wells microplate against selected bacteria and fungi strains while the cytotoxicity was assessed using brine shrimp lethality assay. All the extracts except water inhibi... see more
Uju Dorothy Iliemene, Sunday Ene-Ojo Atawodi
Methanolic extract of Dioclea reflexa seed was investigated following acute or chronic carbon tetrachloride intoxication in male albino rats. In the acute experiment, rats were pre-treated with extract at 5 mg/kg for three days before administration of ca... see more
Aftab Ullah, Mahmood Ahmad
The main purpose of this study was to determine the in vivo hepatoprotective activity of the ethanol extract of whole plant extract of Chenopodium murale (500 and 750 mg/kg; orally) in carbon tetrachloride-induced (0.75 mL/kg; subcutaneously) hepatotoxic ... see more
Mohammad Saleem, Bilal Ahmed, Muhammad Imran Qadir, . Mahrukh, Maria Rafiq, Mobasher Ahmad, Bashir Ahmad
Discovery of drugs has its roots in medicinal plants that appeal researchers to identify new therapeutical entities from plants. The current study was conducted to determine its hepatoprotective activity. The results showed that aqueous methanolic extract... see more
. Channabasava, Melappa Govindappa
All parts of Tabebuia argentia were used for isolation and identified the lapachol producing endophytes were used for evaluation of in vitro cytotoxicity (antimitotic, antiproliferative, determination of cell viability, DNA fragmentation). Five endophytes... see more