36 articles in this issue
Jie Yao, Lin Cong, Benli Zhu, Ting Wang
The purpose of this study is to test the effects of Dietary Approaches to Stop Hypertension (DASH) diet plan on pregnancy outcomes patients with gestational diabetes mellitus. This randomized controlled clinical trial was performed among 33 women diagnose... see more
Ke Li, Wei Lin, Li-Jun Wu, Qiang Qi, Guo Liang Shen, Jian Jiang Liu, Wei Xin Chen, Jun Xu, Hangen Qian, Xiao Yu Zhao
We expounded the effect of intravenous arginine on the healing of human skin graft donor sites. This randomized study was double blind and controlled by placebos from October 2012 to May 2015. Nine patients were selected into the ... see more
Appaji Mahesh Ashwini, Latha Puttarudrappa, Belagumba Vijaykumar Ravi, Mala Majumdar
The aim of the present study was to investigate the GC-MS analysis, phytochemical screening, anti-oxidant, thrombolytic and anti-inflammatory activities of methanol extract of leaves of Exacum bicolor. FTIR analysis confirmed the presence of alcohol, phen... see more
Muhammad Aslam, Nuzhat Sultana
The advantageous effects of Vitis vinifera juice on depressive model mice were examined utilizing a blend of behavioral evaluations and biogenic amine neurotransmitter estimations. During the behavioral evaluations, immobility time on the forced swimming ... see more
Bin Zhou, Qiang Fu, Sha-Sha Song, Hong-Li Zheng, Yu-Zhen Wei
The aim of this study was to examine the anticancer effects of schizophyllan (a -D-glucan) against the growth of rat CNS-1 glioma cells and preliminarily assess its effect on inducing apoptosis and blocking cell cycle. In order to evaluate its inhibitory ... see more
Alia Erum, Sajid Bashir, Shazia Saghir
Arabinoxylan is a polysaccharide of Plantago ovata, an indigenous plant of Pakistan and several European countries. In the present investigation arabinoxylan isolated from P. ovata husk was chemically modified i.e., carboxymethylated and was converted int... see more
Datta Madamwar, Avani Kaushal, Dipak K. Patel, Swati N. Desai, Kapil Upadhyay, Ranjitsinh Devkar
Phycoerythrins from various cyanobacterial sources have been extensively studied globally for their therapeutic potentials. This study shows the apoptotic potential of cyanobacterial phycoerythrin isolated, purified and characterized from marine Lyngbya s... see more
Juan Tan, Li Shenghua, Junying Zeng, Xianjin Wu
The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitrohepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and... see more
Da-Wei Li, Long Meng, Kui-Xing Zhang, Wei-Ke Zhang
The objective was to determine the antiproliferative and apoptotic effects of theaflavin-3-gallate in human non-small cell lung cancer cells (A-549) along with determining the effect on cell cycle phase distribution, cell migration and invasion. Cell viab... see more
Yu-Xian Qian, Rui Yu, Shi-Rong Qin
Breast cancer is the most common type of cancers and second primary cause of death among women. Insulin-like growth factor I (IGF-1) signaling pathway plays a vital role in cancer cell survival, proliferation, chemotaxis and angiogenesis. In this study, t... see more
. Alamgeer, Umme Habiba Hasan, Ambreen Malik Uttra, Shahid Rasool
The present study was commenced to evaluate the anti-arthritic effect of 70% methanol extract and n-butanol and aqueous fractions of Berberis calliobotrys using both in vitro and in vivo arthritis models. Extract and fractions were investigated in vitro f... see more
Jian-Ming Li, Wu-Yin Li, Man-Yu Huang, Xiao-Qiang Zhang
Human osteosarcoma is the most prevalent primary malignant bone tumor with high frequency of invasion and metastasis. Strong resistance coupled with toxicity of the currently available chemotherapeutic drugs poses challenge in treatment. The study aimed t... see more
Sarfaraz Ahmed, Ramzi A. Mothana, Adnan J. Al-Rehaily
The present study was designed to investigate the hypoglycemic and anti-diabetic potential of Oncocalyx glabratus. The extracts and fractions of plant were administrated orally to mice at a dose of 400 mg/kg. The hypoglycemic effect, glucose tolerance tes... see more
Khalid Hussain Janbaz, Waseem Ullah Khan, Fatima Saqib, Mamoona Khalid
Viola odorata is traditionally used in the management of gastrointestinal, respiratory and vascular disorders. The present study was undertaken to validate its folkloric uses. The application of V. odorata to spontaneous contractions in isolated rab... see more
Jing-Wei Zhang, Gong-Ling Wen, Lei Zhang, Dong-Mei Duan, Zhong-Hai Ren
A drimane type sesquiterpenoids, sulphureuine B was isolated from the edible mushroom Laetiporus sulphureus and its antiproliferative properties were investigated using U-87MG glioma cells. It was observed that sulphu-reuine B-induced apoptosis in U-87MG ... see more
Antara Ghosh, Sujan Banik, Md. Ariful Islam
Xanthium indicum is an important medicinal plant traditionally used in Bangladesh as a folkloric treatment. The current study was undertaken to evaluate thrombolytic, anthelmintic, anti-oxidant, cytotoxic properties with phytochemical screening of methano... see more
Irfan Ahmad Rather, Vivek K. Bajpai, Nam Gyeong-Jun
Animal model of intestinal inflammation is of paramount significance that aids in discerning the pathologies underlying ulcerative colitis and Crohns disease, the two clinical presentations of inflammatory bowel disease. The 2,4,6-trinitrobenzene sulfonic... see more
Musaddique Hussain, Shahid Masood Raza, Abdul Majeed
Jatropha gossypifolia is used in folkloric system to manage emesis and gastrointestinal motility disorders such as constipation and diarrhea. The present study was undertaken to provide pharmacological evidences for these folkloric uses by in vivo and in ... see more
Shruti Shukla
In this investigation, a scanning electron microscopy (SEM) method was used to examine the morphostructural changes in bacterial cells induced by antimicrobial agents. SEM-based visual approach is referred the study of bacterial cells and their physiologi... see more
Krishnan Akilandeswari, Kandasamy Ruckmani
In the present study, the antispasmodic drug mebeverine hydrochloride and the antiulcer drug troxipide were tested for their possible antibacterial properties in vitro. The antimicrobial assays of the above drugs were determined with ampicillin, penicilli... see more
Palak A. Shah, Gaurang B. Shah
Uricosuric activity of different extracts of Tinospora cordifolia was studied in hyperuricemia induced in albino Wistar rat using potassium oxonate. The uric acid level in serum and urine were measured. Uricosuric activity was also evaluated using p... see more
Farman Ali Khan, Abdul Khaliq Jan, Nasir Mehmood Khan, Nayab Ali Khan, Shahnaz Khan
Buddleja asiatica essential oil from the leaves by hydrodistillation was subjected to gas chromatography/mass spectrometery analysis which revealed the presence of 17 constituents out of which 14 were identified as: four monoterpenes hydrocarbons, four ox... see more
Xin Song, Chang-Chun Liu, Yu-Rong Hong, Xiao-Cong Zhu
The objective of this study was to determine the anticancer and apoptotic effects of a novel oleanolic acid methyl vanillate derivative in human cervical cancer cells (HeLa). We also evaluated effect of the compound on reactive oxygen species (ROS) genera... see more
Jun Li, Ze-Qing Xu, Ling Bao, Zhi-Cao Li, Jia-Xiang Qu
The present study was taken as an effort to assess the effects of paeonol on diabetic cardiomyopathy. Diabetes was induced in separate groups of Sprague-Dawley rats using streptozotocin. Treatment group animals received paeonol (50, 100 or 200 mg/kg body ... see more
Mukesh Kumar Kumawat, Dipak Chetia
Seven novel dispiro-1,2,4,5-tetraoxane derivatives were synthesized and characterized by a number of analytical and spectroscopic techniques. The molecules were subsequently screened for in vitro antimalarial activity against chloroquine resista... see more
Krishnamoorthy Rajkumar, Ramaswamy Malathi
The aim of this study was to investigate the phytochemical constituents, gas chromatography-mass spectrometry (GC-MS) analysis and antimicrobial activity of Coleus forskohlii. The different solvents such as ethanol, chloroform, acetone and aqueous ex... see more
Li-Guang Yang, Xiang-An Tian, Xiao-Yan Li, Jian-Guo Huang, Nai-Qing Liu, Qin-Li Sun
In the present study, the effect of trolox on human colon cancer cell lines was investigated. The results revealed that trolox treatment caused inhibition of cell growth in T84 and HCT-15 colon cancer cell lines in a dose-dependent manner. The inhibition ... see more
Jin-Jin Guo, Ying-Jie Li, Lu-Lu Xin
Despite advances in conventional therapies, treatment of prostate cancer is still a challenge. The study aims to assess the possible anti-cancer effects of tangeretin, a dietary flavonoid on human prostate cancer cells (DU145, PC3, LNCaP). Tangeretin (25,... see more
Xiao-Yu Dai, Yong-Ming Yu, Zheng-Fang Kong, Yi-Sheng Cao, Dan-Dan Huang, Xiao-Rong Hu, Zuo-An Huang, Yang-Yang Xie, Shun Zhang
Effective immunomodulator and pro-inflammatory cytokine, Tumor necrosis factor-a (TNF-a) are considered to be responsible for connecting autoimmune pathological process and contagious diseases. TNF-a stimulates the C-X-C motif chemokine 10 (CXCL10) expres... see more
Zhe Zhang, Ying Shen, Jian Wu, Lin Cai
In the present study, the effect of cucurbitacin B and cerulenin combination on osteosarcoma was investigated to develop an effective treatment regimen. The IC50 values of cerulenin and cucurbitacin B combination in the proportion of 1:1, 1:2 and 2:1 were... see more
Mallappa Kumara Swamy, Uma Rani Sinniah
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Venkatramanan Varadharajan, Sethupathi Shanmugam, Arulvel Ramaswamy
Ji-Heng Hao, Dian-Feng Hu, Li-Mei Mao, Shi-Gang Zhang, Ji-Yue Wang, Gang Li
The present study was performed to investigate the effect of 2-fluorobenzaldehyde retinoic acid conjugate on activation of STAT3 pathway in human glioma cells. The results revealed that the compound exhibited inhibitory effect on the activation of STAT3 i... see more
Liu-Bing Li, Subin Lin, Jun Yan, Qian-Liang Wang, Zhi-Ying Fan, Qi-Rong Dong, Jian-Zhong Qin, Zong-Gang Xie
Osteosarcoma shows resistance to chemotherapy and many side effects. The ethyl acetate fraction of ethanolic extract of Chrysophyllum cainito was taken in the present work. The extract was characterized for its phenolic content, antioxidant capacity (ferr... see more
Shahid Rasool, Farrukh Zia Khan, Mobasher Ahmad
The purpose of this study was to evaluate the anticonvulsant, antimicrobial and hemolytic effect of Aitchisonia rosea. The anticonvulsant effect was studied at doses 400 and 800 mg/kg against pentylenetetrazole, strychnine and picrotoxin-induced seizures ... see more
Yang Wang, Zheng Fei Zhu, Wei Jun Pan, Zhe Xu
This study aims to evaluate the efficacy and safety of goserelin combined with chemotherapy for premenopausal women with breast cancer. Literatures were extracted from databases including Excerpta Medica Database, Springer, Pubmed, China National Knowledg... see more