28 articles in this issue
Ning Zeng, Hong Qiu, Min Wu, Yi Xu, Hai-Ping Wang, Ying Zhan
Article is withdrawn by the Authors
Amara Mumtaz, Aamer Saeed, Nighat Fatima, Muhammad Dawood, Hummera Rafique, Jamshed Iqbal
Imidazole and its derivatives are the pharmacological significant scaffolds with the broad spectrum of activities can be synthesized in the laboratory in the single step by the action of the catalyst. The current review summarizes the role ... see more
Alireza Mirkheshti, Elham Memary, Hamed Shafiee, Mastaneh Dahi
This study was performed to assess the effect of dexmedetomidine on the level of N-terminal proB-type natriuretic peptide (NT-pro-BNP) in patients undergoing major orthopedic surgery. Patients undergoing general anesthesia for femoral shaft fracture surge... see more
Xian-De Cao, Hui-Min Zheng
The aim of the present study was to investigate the role of zerumbone on the proliferation, cell cycle arrest and cell death in DU-145 prostate cancer cell lines. The MTT assay revealed that zerumbone (20 µM) reduced proliferation of DU-145 cells to 39.0%... see more
. Alamgeer, Hira Asif, Shahid Rasool
This study was focused with the aim to investigate the antithrombotic potential of Berberis calliobotrys. Aqueous-methanolic extract and various fractions showed significant (p<0.05-0.001) increase in prothrombin, activated partial thromboplastin and c... see more
Abdul Jabbar Shah, Ishfaq Ali Bukhari, Anwarul Hassan Gilani
This study was aimed to investigate the effect of the extract of Mentha longifolia on blood pressure and the possible mechanisms. In anesthetized rats, the crude extract of M. longifolia and aqueous and chloroform fractions caused a dose-dependent fall in... see more
Ying Li, Na Han, Zhuo Chen, Xing Li
This review evaluates the effectiveness and safety of injection of shenqi fuzheng with chemotherapy in the treatment of breast cancer in China. The study included 20 randomized clinical trials (RCTs) involving 1,609 patients. It was shown that shenqi fuzh... see more
Hemant Arunrao Sawarkar, Pranita P. Kashyap, Ajit Kumar Pandey, Mukesh Kumar Singh, Chanchal Deep Kaur
Leaf juices as well as leaves of Barleria prionitis and Barleria grandiflora are being used by rural people across various regions of India in the treatment of oral ailments such as dental troubles, gum ailments, pyorrhoea, dental carries and mouth ulcers... see more
Zahra Rabiei, Zahra Lorigooini, Mahmoud Rafieian Kopaei
The aim of the present study was to investigate the effect of hydroalcoholic extract of Borago officinalis on morphine withdrawal syndrome in mice. Morphine-dependent group received morphine for nine days and then received naloxone via intraperitoneal inj... see more
Naveed Aslam, Khalid Hussain Janbaz, Qaiser Jabeen
In order to rationalize the traditional uses of Asphodelus tenuifolius in cardiovascular complaints, aqueous-ethanol extract of the plant was investigated for hypotensive and diuretic activities using in vivo and in vitro models. Intravenous administratio... see more
Ning Xia
The present study was aimed at to demonstrate the antitumor effects of syringin in HeLa human cervical cancer cells. Its effects on apoptosis, cell cycle phase distribution as well as on cell migration were also examined. The effect on cell proliferation ... see more
Vivek K. Bajpai, Rajib Majumder, Jae Gyu Park
Chromatographic techniques have significant role in natural products chemistry as well as contribute dramatically in the discovery of novel and innovative compounds of pharmaceutical and biomedical importance. This study focused on step-by-step visual dem... see more
Irfan Ahmad Rather, Vivek K. Bajpai, Jonghun Han, Gyeong-Jun Nam
Psoriasis is a skin disorder characterized by skin inflammation and plaques. Induction of psoriasis in animal model include following steps: a) Selection of animal model, b) Hair removing from the back or ear, c) treatment of skin with Aldara, a cream con... see more
Vivek K. Bajpai, Na-Hyung Kim, Kangmin Kim
Derivatization is the process by which a compound is chemically changed, that has properties more amenable to a particular analytical method. Some samples analyzed by Gas-chromatography and Mass-spectrometry (GC-MS) require derivatization in order to make... see more
Li Lin, Xiao-Ling Cheng, Ming-Zhe Li, Tao Wang, Min-Hai Dong, Zhen-Yu Wang, Min Liao
The main purpose of the current study was to study the antitumor effects of iridomyrmecin against human cervical cancer cells (HeLa). Its effects on apoptosis induction, cell cycle phase distribution, PI3K/Akt signalling pathway and long non-coding RNA (l... see more
Quan Liang, Qiang Fu, Wei Li, Jiacong You, Zhanchao Zhao
The aim of this study was to compare the efficacy and safety of trastuzumab versus the combination of trastuzumab and lapatinib added to neoadjuvant chemotherapy for HER2 positive breast cancer. PubMed, MEDLINE, The Cochrane Library, Web of Science and ne... see more
Long Yang, Xiu-Juan Dong
The role of the P2X7R in developing acute kidney injury is unknown. In this study, we developed acute kidney injury mouse model system using 0.75% adenine and examined for renal damage using histology on day 2 and day 4. P2X7 antagonist (A438079) wa... see more
M. Punnam Chander, Paluru Vijayachari
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Shanmuga Sundaram Rajagopal, Gomathi Swaminathan, Vijayabaskaran Manickam, Sambathkumar Ramanathan
Sivaperumal Gopalan, Kannnan Kulanthai, Gnanavel Sadashivam, Perumal Pachiappan, Sowmiya Rajamani, Deepak Paramasivam
There is a need to investigate the new sources of antimalarial drugs which are more effective against Plasmodium falciparum. The present study was undertaken to evaluate the in vitro antiplasmodial activity of vasicinone, vasicine and 9-oxo-1, 2, 3, 9-tet... see more
Sundaram Dhivya, Subbiah Latha, Palanisamy Selvamani
Cadaba indica, a component of traditional siddha medicine, is used for the therapy of gonorrhea, inflammation, eczema etc. The present study shows that it exhibited acetylcholinesterase inhibitory activity (up to 81.5 ± 1.5%) at the concentration of 3 mg/... see more
Fayaz Ali Larik, Aamer Saeed, Pervaiz Ali Channar, Hammad Ismail, Erum Dilshad, Bushra Mirza
An efficient solvent-free synthesis of a 10-member library of octanoyl linked substituted aryl thioureas was accomplished successfully. The octanoyl isothiocyanate was freshly prepared in excellent yield and purity by the reaction of potassium thiocyanate... see more
Soosaimanickam Carmel Punitha, Muthu Rajasekaran
The present study examined the cardioprotective role of methanol extract of the edible mushroom Volvariella volvacea against oxidative stress in hyperglycemic rats. Rats divided into 6 groups were administered with nicotinamide and streptozotocin intraper... see more
Mehran Mesgari Abbasi, Hadi Valizadeh, Hamed Hamishehkar, Maryam Bannazadeh Amirkhiz, Parvin Zakeri-Milani
P-glycoprotein (P-gp) is a membrane transporter responsible for the active efflux from the cell. Inhibition of the activity may lead to clinically significant drug-drug interactions. This study was performed to investigate the effects of atorvastatin and ... see more
Vineetha M. Shrikanth, Bhavya Janardhan, Sunil S. More
Canthium parviflorum is used in the traditional therapy to treat snakebite victims. In the present study, partially purified methanol root extract of C. parviflorum was used for the neutralization of Eachis carinatus and Naja naja venom. The extract inhib... see more
Jannatul Ferdoush, Kohinoor Parveen, Maliha Ata, Fahim Hasan Reza, Md. Sayedur Rahman
The study was aimed to evaluate the knowledge, perception and prepared-ness of the 4th year students of three medical colleges of Bangladesh during January 2016. The questionnaire was designed to evaluate knowledge, perception and preparedness about antim... see more
Ayyappadasan Ganesan, Amutha Mahesh, Jeya Prakash Sundararaj, Kalaiselvi Mani, Ponmurugan Ponnusamy
The core objective of this study was to investigate the in vitro anti-oxidant and antihyperglycemic effect of the ethanol extract of Parmotrema hababianum in streptozocin-induced diabetic rats for 42 days. The extract showed nearly all anti-oxidant activi... see more
Nadia Bintha Khalil, Mir Misbahuddin, Abu Naser Ibne Sattar
The aim of the present study was to examine the involvement of skin bacteria in the pathogenesis of keratosis. Skin swab of five different sites (palm, dorsum of the hand, chest, axilla and alar crease) from arsenic unexposed volunteer (n = 15), arsenic e... see more