19 articles in this issue
Mutiu Idowu Kazeem, Semawon Mauton Ogungbe, Gbemisola Morounke Saibu, Oluwaseyi Mayode Aboyade
Inhibition of some carbohydrate metabolizing enzymes is one of the modes of action of antihyperglycemic agents. The aim of this study was to investigate the in vitro inhibition of a-amylase and a-glucosidase by extracts of N. tabacum leaf. Powdered leaves... see more
Deepa Murugesan, Renuka Devi Ponnusamy, Dhanalakshmi Karur Gopalan
The aim of the study is to identify the phytocompounds with anti-inflammatory properties from the methanolic leaf extract of Vitex negundo and also to find the inhibitors of cyclooxygenase-2 (COX-2) enzyme through molecular docking. GC-MS was performed fo... see more
Vivek K. Bajpai, Sun Chul Kang
The objective of this study was to confirm the antimycotic potential of a diterpenoid compound taxoquinone, isolated from Metasequoia glyptostroboides against pathogenic isolates of Candida species. The taxoquinone (100 mcg/disc) displayed potential antic... see more
Nimmakayala Sridhar, Bondada V.V.S. Surya Kiran, Donthamsetti Tharaka Sasidhar, Lakshmi Kanta Kanthal
Antimicrobial activity of methanolic extracts of plants was screened by disc diffusion assay against four bacteria and four fungal cultures. Streptomycin (10 ?g/disc) and nystatin (10 ?g/disc) are used as standards for bacteria and fungi respectively. Min... see more
M. Imran Qadir, Muhammad Sajid Al Murad, Muhammad Ali, Mohammad Saleem, Ammad Ahmad Farooqi
The hepatoprotective activities of Cestrum nocturnum (Queen of Night) was evaluated against the paracetamol induced hepatotoxicity in the mice. Aqueous ethanol (30:70) extract of plant was obtained by maceration. Results showed that aqueous ethanol extrac... see more
Flora Mohamadizadeh, Majid Afkhami, Maryam Ehsanpour, Amir Houshang Bahri
Within the frame of a biodiversity and bioactivity study of marine macro organisms from the Persian Gulf, three hard coral species extracts were investigated for cytotoxic, antibacterial and antifungal activities against five human pathogenic microorganis... see more
Nafisa Rashid, Mir Misbahuddin, Zubaida Khatoon Choudhry, Ahmed Abu Saleh, Abu Naser Ibne Sattar
The role of probiotics supplementation for 12 weeks on the colony count of Escherichia coli in the stool of moderate palmar arsenical keratosis (14), arsenic exposed controls (15) and healthy volunteers (9) were studied. The mean colony counts of E. coli ... see more
Swarmita Afreen, Md. Sayedur Rahman
The present study was conducted to evaluate the adherence to treatment guidelines in Bangabandhu Sheikh Mujib Medical University. The study assessed the awareness of prescribers, adherence to treatment guidelines and reasons for non-adherence. A questionn... see more
Mohammad Saleem, Mahrukh Karim, Muhammad Imran Qadir, Bilal Ahmed, Maria Rafiq, Bashir Ahmad
Vicia sativa is traditionally used medicinal plant in skin infections, asthma, bronchitis, urinary diseases and also used as antiseptic, anti-poison, aphrodisiac, anti rheumatic and antipyretic. In the present study n-hexane extract of V. sativa was evalu... see more
Stalin Selvaraj, Sampathkumar Palanisamy
The present study evaluated the hypoglycemic effect of brown algae Sargassum longiotom in alloxan-induced diabetic rats. After the treatment with S. longiotom extract, there is a significant reduction (p<0.001) in blood glucose when compared with the d... see more
M. Imran Qadir, Muhammad Ali, Muhammad Ali, Mohammad Saleem, Muhammad Hanif
Traditionally Viola odorata is used for liver protection. To provide scientific support to its traditional use, aqueous methanolic extract of V. odorata (250 mg/kg and 500 mg/kg) was given to mice intoxicated with paracetamol. Obtained results demonstrate... see more
Nabi Shah, Abdul Jabbar Shah, Manzoor Ahmed, Anwar Hassan Gilani
The aim of the present work was to study the functional nature of the potential spasmolytic effect of the crude extract of Sauromatum guttaum. It was found positive for the presence of alkaloid and tannins. In isolated rabbit jejunum preparation, S. gutta... see more
Lalit Mohan Nainwal, Pratap Parida, Aparoop Das, Parth Sarathi Bairy
Topoisomerase (topo) IIa is a homodimeric protein catalyzes topological vicissitudes by adding or by soothing super coiling transpiration, occurs in human DNA during DNA replication as an outcome chromosome segregation and condensation occurs during meios... see more
Md. Sayedur Rahman, Sharmila Huda
The present study was designed to understand Bangladesh situation about antimicrobial resistance. Half of the Escherichia coli, Staphylococcus aureus, Pseudomonas and Klebsiella showed resistance against older and common antimicrobials. Most (50%) common ... see more
Bhaskor Kolita, Dhrubajyoti Gogoi, Partha Pratim Dutta, Manobjyoti Bordoloi, Rajib Lochan Bezbaruah
Antibiotic resistance is a major challenge to combat tuberculosis. Several reports of antibiotic resistance strains of Mycobacterium tuberculosis is strongly demanding the need of new and alternative antibiotics for its inhibition. Therefore, current inve... see more
- Alamgeer, Mehwish Nawaz, Taseer Ahmad, Muhammad Naveed Mushtaq, Asma Batool
In the present study, the hepatoprotective activity of aqueous and ether extracts of Thymus linearis (250 and 500 mg/kg orally) was evaluated against carbon tetrachloride- and paracetamol-induced hepatic damage in mice. Serum levels of alanine aminotransf... see more
Xin Sui, Zhizhong Sun, Weiwei An, Kai Cheng, Shougang Jiang, Gong Xianfeng
Anti-proliferative and apoptosis-inducing effects of 2,4,3?,4?-tetramethoxy-biphenyl (TMBP) on human gastric cancer MGC-803 cells were investigated. The molecular mechanisms of TMBP-mediated tumor cell death were detected by clonogenic assay, staining wit... see more
Malik Saadullah, Bashir Ahmad Chaudary, Muhammad Uzair, Khurram Afzal
The antidiabetic activity of Conocarpus lancifolius extract was investigated in vitro, as alpha glucosidase inhibition and in vivo as alloxan induced diabetic rabbits with other biochemical parameters (LDL, HDL, SGPT, SGOT, cretinine, urea and triglycerid... see more
Bino Kingsley, K. P. Arun, Stalin Selvaraj, Brindha Pemiah
Present study evaluates the anti-diabetic activity of S. tetragonam LC-MS/MS experiments showed the presence of two novel molecules C1 and C2, which were further taken for in silico study against PPAR?. Cell culture studies with A431 cells in the pre... see more