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302  Articles
1 of 31 pages  |  10  records  |  more records»
SummaryIntroduction and objective: Cancer arises from genetic and epigenetic changes in the cell. Indication of the direct causes of cancer is no doubt very difficult, because the process of carcinogenesis is a multi-level and multi-stage. Knowledge of ex... see more

Introduction and aim.Reactive oxygen species and increased oxidative stress cause a series of disorders in the metabolism of the cell. Initiate adverse changes to the structure of DNA, lipids and proteins. The purpose of this article is to introduce the c... see more

Features of lipid peroxidation processes and antioxidant system in spleen tissue of white rats in experimental carcinogenesis and application of cytostatics were studied in experimental research. In DMH-induced cancerogenesis it was found a significant in... see more

Features of lipid peroxidation processes and antioxidant system in spleen tissue of white rats in experimental carcinogenesis and application of cytostatics were studied in experimental research. In DMH-induced cancerogenesis it was found a significant in... see more

Objective: The present study was aimed to test the efficacy of pomegranate fruit extract to induce apoptosis in the artificially induced tumor cells in mice. Method: Adult male LAKA-UK mice (30-40g) were divided into four groups, viz. control, AA, PFE and... see more

The effect of individual oncogene on diverse cell types could be studied by using transgenic mice. The expression of transgene is mainly determined by the regulatory sequences chosen. Fifty four v-H-ras transgenic FVB/N mice and 54 parental FVB/N mice wer... see more

Polycyclic aromatic hydrocarbons are known carcinogens used in rodent experimental models. In this study, the carcinogen DMBA (7,12-dimethylbenzanthracene) was administered by gavage, diluted in corn oil, to female BALB / c mice at hebdomadary doses of 1 ... see more

Bystander or non-targeted effect is known to be an interesting phenomenon in radiobiology. The genetic consequences of bystander effect on non-irradiated cells have shown that this phenomenon can be considered as one of the most important factors involved... see more

In the present study, we examined the cytotoxic effect of Conyza bonariensis (methanolic extract). The skin carcinogenesis was induced in two stages, first, applying tumor initiator, 7-12-dimethyl benz(a)antheracene and thereafter applying croton oil, a t... see more

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