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4.081  Articles
1 of 409 pages  |  10  records  |  more records»
Cancer accounts as one of the leading causes of morbidity and mortality. Recent studies focus on the efficiency of phytochemicals in cancer therapy. Influence of quercetin, a flavonoid on the effect of ?d T cells and Wnt/ß-catenin signalling pathway in hu... see more

Breast cancer is the second most common cancer among women worldwide. The Wnt–ß-catenin pathway appears to be deregulated in most can­cer cells including breast cancer. The role of zerumbone, the active sesquiter­pene from Zingiber zerumbet Roscoe, on the... see more

Increasing evidences show that XRCC6 (X-ray repair complementing defective repair in Chinese hamster cells 6) was upregulated and involved in tumor growth in several tumor types. However, the correlation of XRCC6 and human osteosarcoma (OS) is still unkno... see more

The technology to derive embryonic and induced pluripotent stem cells from early embryonic stages and adult somatic cells, respectively, emerged as a powerful resource to enable the establishment of new in vitro models, which recapitulate early developmen... see more

Background: integrins have been associated with the development of chemotherapy resistant tumour cells, mostly those of hematopoietic origin, by mediating the binding to the extracellular matrix. The relevance for solid tumour cells and the underlying mec... see more

The regenerative ability of planarians depends largely on its complex signaling pathways. The Wnt pathway regulates the A/P polarity formation after regeneration, while the MAPK pathway plays a role in regeneration. This experiment uses various drugs to d... see more

Objective: The aim of this study is to investigate in vitro effects of an antihelminthic drug niclosamide on human ovarian carcinoma cell line OVCAR-3. Methods: MTT assay was applied to investigate the cytotoxic effects of niclosamide on the cells. ß-cate... see more

Colorectal cancer is one of the leading causes of death worldwide. Wnt/beta-catenin signalling pathway plays a central role in normal cellular responses, making it a potent target in cancer therapy. Study was taken to assess whether ellagic acid modulates... see more

Osteosarcoma is one of the most common malignant bone tumors in children and adults. Till this date, molecular mechanism behind the growth and invasiveness of osteosarcoma is poorly understood. Wnt5a plays an important role in the oncogenesis and cancer m... see more

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