Journal title

Genes  

ISSN: 2073-4425    frecuency : 4   format : Electrónica

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Volume 10 Number 1 Part January Year 2019

30 articles in this issue 

Deborah J. Marsh and Kristie-Ann Dickson

There is growing evidence highlighting the importance of monoubiquitination as part of the histone code. Monoubiquitination, the covalent attachment of a single ubiquitin molecule at specific lysines of histone tails, has been associated with transcriptio... see more

 

Chao Yang, Yu-Tian Wang and Chun-Hou Zheng

Availability of diverse types of high-throughput data increases the opportunities for researchers to develop computational methods to provide a more comprehensive view for the mechanism and therapy of cancer. One fundamental goal for oncology is to divide... see more

 

Christian Bronner, Mahmoud Alhosin, Ali Hamiche and Marc Mousli

DNA methylation, catalyzed by DNA methyltransferases (DNMTs), is an epigenetic mark that needs to be faithfully replicated during mitosis in order to maintain cell phenotype during successive cell divisions. This epigenetic mark is located on the 5′... see more

 

Jing Zhang, Xin Xu, Yan Liu, Lin Zhang, Jack Odle, Xi Lin, Huiling Zhu, Xiuying Wang and Yulan Liu

This study was conducted to elucidate the biological effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on cell proliferation, differentiation and gene expression in C2C12 myoblasts. C2C12 were treated with various concentrations of EPA... see more

 

Perot Saelao, Ying Wang, Ganrea Chanthavixay, Rodrigo A. Gallardo, Anna Wolc, Jack C. M. Dekkers, Susan J. Lamont, Terra Kelly and Huaijun Zhou

Newcastle disease virus (NDV) is a highly contagious avian pathogen that poses a tremendous threat to poultry producers in endemic zones due to its epidemic potential. To investigate host genetic resistance to NDV while under the effects of heat stress, a... see more

 

Lin Liu, Lin Tang, Xin Jin and Wei Zhou

With the continuous accumulation of biological data, more and more machine learning algorithms have been introduced into the field of gene function prediction, which has great significance in decoding the secret of life. Recently, a multi-label supervised... see more

 

Jan Gorodkin

RNA structure often plays a key role in determining the function of non-coding and coding transcripts [...]

 

Marc Woodman, Ilsa L. Haeusler and Louis Grandjean

There are an estimated 10 million new cases of tuberculosis worldwide annually, with 282,000 new or relapsed cases each year reported from the Americas. With improvements in genome sequencing technology, it is now possible to study the genetic diversity o... see more

 

Sorina Dinescu, Simona Ignat, Andreea Daniela Lazar, Carolina Constantin, Monica Neagu and Marieta Costache

In contrast to the amazing exponential growth in knowledge related to long non-coding RNAs (lncRNAs) involved in cell homeostasis or dysregulated pathological states, little is known so far about the links between the chemical modifications occurring in l... see more

 

Ditipriya Hazra, Clément Chapat and Marc Graille

The control of gene expression is a multi-layered process occurring at the level of DNA, RNA, and proteins. With the emergence of highly sensitive techniques, new aspects of RNA regulation have been uncovered leading to the emerging field of epitranscript... see more

 

Genes Editorial Office

Rigorous peer-review is the corner-stone of high-quality academic publishing [...]

 

Natalia Ledo HusPhillips and Tania L. Roth

The use of non-human animals in research is a longstanding practice to help us understand and improve human biology and health. Animal models allow researchers, for example, to carefully manipulate environmental factors in order to understand how they con... see more

 

Junliang Shang, Qian Ding, Shasha Yuan, Jin-Xing Liu, Feng Li and Honghai Zhang

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Identifying characteristic genes of PTC are of great importance to reveal its potential genetic mechanisms. In this paper, we proposed a framework, as well as a measure named Nor... see more

 

Wenjing Zhang, Neng Huang, Jiantao Zheng, Xingyu Liao, Jianxin Wang and Hong-Dong Li

The advent of third-generation sequencing (TGS) technologies, such as the Pacific Biosciences (PacBio) and Oxford Nanopore machines, provides new possibilities for contig assembly, scaffolding, and high-performance computing in bioinformatics due to its l... see more