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30.327  Articles
1 of 3.034 pages  |  10  records  |  more records»
The aim of our study is the integration of a multidisciplinary approach for Prader- Willi and Angelman syndromes, distinct genomic diseases, with a neurodegenerative component. The main lesion is localized on the 15q11.2-13 chromosome caused during genito... see more

Brain aging is linked to certain types of neurodegenerative diseases and identifying new therapeutic targets has become critical. Melatonin, a pineal hormone, associates with molecules and signaling pathways that sense and influence energy metabolism, aut... see more

Skin undergoes continuous renewal throughout an individual’s lifetime relying on stem cell functionality. However, a decline of the skin regenerative potential occurs with age. The accumulation of senescent cells over time probably reduces tissue re... see more

BACKGROUND: Mitochondria became a driving force in evolution due to their ability to manufacture adenosine triphosphate (ATP) through respiration. The functioning of mitochondria within eukaryotic cells has evolved dramatically as a result of evolution. R... see more

BACKGROUND: Mitochondria became a driving force in evolution due to their ability to manufacture adenosine triphosphate (ATP) through respiration. The functioning of mitochondria within eukaryotic cells has evolved dramatically as a result of evolution. R... see more

Based on  preliminary reports, case studies (Roy, 2000; Yan et al., 2002b)  as well as  an in vitro experiment conducted at University of California,  San Diego (Yan et al, 2002a)   we propose several new tests designed to co... see more

Multiple sclerosis (MS) is a complex disease characterized by autoimmune demyelination of the myelin sheath of the central nervous system. Varying degrees of disability result from disruptions in neural, physical, and psychological processes. No clear cau... see more

In vivo, cells are surrounded by a three-dimensional (3-D) organization of supporting matrix, neighboring cells and a gradient of chemical and mechanical signals (Antoni, et al., 2015). However, the present understanding of many biological processes is ma... see more

Riassunto: Il presente contributo intende esplorare la possibilità di una ridefinizione del concetto di libertà alla luce di un quadro naturalistico di riferimento. Per un verso, si rileva come le concezioni della libertà che cercano di salvaguardare una ... see more

1 of 3.034 pages  |  10  records  |  more records»