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189  Articles
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Background: Fisetin, a natural potent flavonoid, has various beneficial, pharmacological activities. In this study, we investigated expression changes of the fisetin regulating genes in lipopolysaccharide (LPS)-treated RAW264.7 cells and explored the role... see more

Paper description:Antidesma bunius fruit exhibits antioxidant properties. Its anticancer activities remain underexplored.We investigated the effects of Antidesma bunius fruit aqueous extract (A. bunius ACE) on the redox status, mitochondrial integrity and... see more

Paper description:Glioblastoma is one of the most fatal and aggressive cancers with unmet clinical needs. Studies in various cell models reported that allicin induces proapoptotic anticancer effects, albeit the mechanism remains unclear.The current study ... see more

Autophagy is a biomolecular system known to play an important role in cell growth, development as well as defense mechanisms, and is also a physiological approach towards homeostasis maintenance. This phenomenon is an intermediary pathway in the pathogene... see more

Background : Pulmonary Pseudomonas aeruginosa infection in cystic fibrosis patients is associated with skeletal muscle atrophy. In this study, we investigated the effects of P. aeurginosa infection and a whey protein-rich diet on skeletal muscle proteolyt... see more

M. tuberculosis (MTB) is an intracelular bacteria that live in the host macrophage cells. Several organs can be affected by tuberculosis but most major illnesses are lung diseases. Immediately after infection, MTB will be phagocytosed by the alveolar macr... see more

The study demonstrates the effect of vernolepin on proliferation and apoptosis in ovarian cancer cell lines. The inhibition of cell growth was significant at 30 ?M concentration after 48 hours in both OVCAR-3 and SK-OV3 cell lines. Phase-contrast microsco... see more

Paper description:Nigella B (NB) is the hydrolysis product of Nigella A (NA) which is extracted from the seeds of Nigella glandulifera Freyn and has been reported to possess several beneficial characteristics, including an anticancer effect.This work demo... see more

TRAPP (transport protein particle) is a large, highly conserved, multi-subunit complex. Four types of TRAPP complexes (I, II, III and most recently IV) have been identified in Saccharomyces cerevisiae. Studies on the roles of TRAPP II, TRAPP III and TRAPP... see more

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