15 articles in this issue
N. Yu. Bondarenko,M. Ye. Blazheyevskiy
The method of caffeine chemilumeniscent determination in coffee beans «Arabica» (Galka Ltd, Lviv, Ukraine) based on reaction of inhibition of chemilumeniscent oxidation of luminol by hydrogen peroxide, catalyzed by blood hemoglobin have been elaborated. I... see more
O. V. Dolzhykova,L. N. Maloshtan
The article considers the influence of vaginal suppositories "Melanizol" based on metronidazole, and tea tree oil on the museum and clinical strains of microorganisms, that may be potential agents of vaginal infections. Established antimicrobial activity ... see more
D. A. Lega,N. I. Filimonova,H. M. Dikaya,V. P. Chernykh,L. A. Shemchuk
Currently, antibiotic resistance is becoming a tremendous threat in treatment of bacterial and fungal infections. Therefore, a topical question is the search of new classes of antimicrobial drugs. The present article is devoted to the study of antimicrobi... see more
R. O. Shcherbyna
In this work we have conducted the synthesis, the establishment of physical-chemical properties and subsequent Pass-screening of possible biological activity for new alkyl derivatives of 4-R-3-(morfolinometylen)-4H-1,2,4-triazole-5-thioles. According to t... see more
A. M. Kovalyova,A. V. Goncharov,A. V. Ochkur
The antibacterial properties of lipophilic, phenolic complexes and dry extract and sedative activity of dry extract obtained from Lamium album (white dead-nettle) herb have been investigated. It is established that white dead-nettle dry extract shows weak... see more
I. A. Lukina,O. V. Mazulin
The composition of the essential oil obtained of Polygonum persicaria L. and was analyzed by GC-MS. The study established the qualitative and quantitative composition of the essential oil content. The total content of essential oil in the herb Polygonum p... see more
O. V. Zarichanska,S. M. Marchyshyn,V. P. Rudenko,O. V. Gamulya
The investigation of anatomy structure of the flower and the leaf of hybrid daylily of “Stella De Oro” variant has been performed for the first time and microdiagnostic features, which can be used for identification of the investigated plant raw materials... see more
L. V. Brun,S. N. Gubar
For the study of quantitative determination of diclofenac sodium, sample preparation of biological objects has been performed. Linear dependence of diclofenac sodium peak area and substance concentration in the solution (5-25 mg/ml) has been proved. The m... see more
D. A. Dorovsky,A. L. Zagayko
Lecithin cholesterol acyltransferase (LCAT) is a key enzyme that catalyzes the esterification of free cholesterol in plasma lipoproteins and plays a critical role in high density lipoprotein (HDL) metabolism. LCAT deficiency leads to accumulation of... see more
A. L. Zagayko,T. A. Briukhanova
The work is devoted to the results of the study of endothelium functional state changes in the rat’s blood under different experimental models of insulin resistance - in particular, modeled by hypercaloric diet with high fructose content or hypercaloric d... see more
A. V. Horbulinska,M. R. Khokhla,H. Ya. Hachkova,N. O. Sybirna
Article contain the results of the yacons leaves and root tubers water extracts and suspensions of yacons root tubers effect on glucose tolerance in animals with experimental diabetes mellitus (EDM). It was shown that the studied yacons extracts and suspe... see more
A. L. Zagayko,O. I. Chumak,V. P. Filimonenko,O. M. Koshevoy
Investigated the pharmacological properties of dry extractof cranberries and blueberries with the addition of L-arginine in experimental metabolic syndrome in rats induced vsokoprotocnah diet. Revealed more pronounced antiatherogenic properties of extract... see more
A. L. Zagayko,A. I. Shkapo,T. O. Briukhanova
As a result of studies have shown that prolonged intraperitoneal injection of dexamethasone in low doses and its combination with high-calorie diet leads to formation of the insulin resistance syndrome in rats. Against of this pathology background was obs... see more
A. L. Zagayko,O. A. Krasilnikova,Mohamed Ahmed Musmari
JNK kinase - group stress-activated kinases that are involved in apoptosis, growth, development and differentiation of cells. JNK kinase activation is observed in the development of inflammatory processes, neurodegenerative disorders, insulin resistance, ... see more