17 articles in this issue
A. L. Zagayko,T. O. Brukhanova
Despite the fact that over the past 50 years there has been a tendency to decrease morbidity and mortality from a stomach cancer, especially in industrialized countries, in the structure of ontological pathology it takes the 4th place on the prevalence an... see more
V. I. Horlachova,L. I. Vyshnevska
For the purpose of further experimental work on the development of composition and technology of medical and cosmetic products in the form of an anti-inflammatory cream investigated the effectiveness of sodium benzoate, phenoxethanol, Eyxil PE 9010, germa... see more
L. V. Lukyanova
Researches of behavioral-emotional reactions are carried out in experiment on laboratory animals at introduction nitrogen-containing organic compounds (carbamazepine, caffeine) and their compositions in the conditions of a formalin edema. The analysis of ... see more
N. G. Vakhnina
The article have been devoted to screening tests hypoglycemic action of 43 new derivatives of malonic and oxalic acids. Studies carried out on rabbits with normal blood glucose. The studied compounds were administered at a dose of 1/20 LD50. Comparison dr... see more
O. V. Tovchiga
This study addressed the influence of Aegopodium podagraria L. (goutweed) aerial part extract (100 mg/kg and 1 g/kg) and tincture (1 and 5 ml/kg) on the course of ethanol-induced as well as thiopental sodium induced narcosis. It has be... see more
R. O. Shcherbyna,O. I. Panasenko,Ye. H. Knysh
In this work we have conducted the synthesis, the establishment of physical-chemical properties and subsequent Pass-screening of possible biological activity for new alkyl derivatives of 4-R-3-(morfolinometylen)-4H-1,2,4-triazole-5-thioles. According to t... see more
S. V. Kalinichenko,O. O. Korotkykh,I. Yu. Tishchenko
The article describes the topical areas of improvement of probiotics, such as: study of the physiology of promising industrial strains in order to select nutrient media for their cultivation; determination of sorption processes of probiotic bacteria... see more
L. O. Yarovenko
This article contains data about morphometric parameters of studies liver tissue in rats of different age periods females with chronic alcoholic liver disease and on the background of pathogenetic correction using quercetin and L-arginine-L-glutamate in t... see more
T. A. Suleymanov,Yusuf Ozkay,C. Y. Shukurov
Derivatives of piperazin-1-dithiocarbamates 4-aniline piperidine were synthesized and their structures were identified by elemental analysis IR, NMR and mass spectroscopy. The biological activity of the synthesized derivatives of dithiocarbamates was inve... see more
G. V. Vovk,M. M. Myga,O. M. Koshovyi,Yu. V. Verkhovodova,I. V. Kireev
On the Ukrainian market there are more than 40 medicines, which contain biological active substances of sage leaves. They essentially includes an essential oil. Wastes from the production of sage essential oil are tons of water distillation extract, so th... see more
I. O. Kolychev,T. O. Krasnikova,A. L. Zagayko,O. M. Koshovyi
Continuing research of biological active substances in bilberry leaves and their products, we paid attention to the fact that the composition of organic acids hasn’t virtually been studied. So, the purpose of our research was studies of organic acids in t... see more
A. M. Kovaleva,A. P. Osmachko,N. V. Kashpur,I. V. Grudko
The screening of antibacterial activity of two complexes of biologically active substances from Veronica longifolia ‘Blaubart’ herb, obtained successively by means of chloroform and ethyl acetate were conducted respect to gram-negative (Escherichia coli, ... see more
L. V. Ocheredko,V. V. Hnatiuk,T. N. Kryuchkova
A phytocomposition based on roots of wild rose for the treatment of functional disorders of the cardiovascular system is designed, the application performance is improved vascular tone and cardiac students with special physical training group who were reg... see more
L. V. Lenchyk,I. V. Senyuk,Bashar Al-Jabbar Ali Sahlani
Content and quantitative composition of the organic acid in plum leaves have been studied by Gas chromatography mass spectrometry on Agilent Technologies 6890 chromatograph with mass spectrometric detector 5973; chromatography column - INNOWAX, capillary ... see more
O. O. Gonchar,O. A. Nazarchuk,D. V. Paliy,I. V. Kovalenko,O. V. Yatsula
In the research the effectiveness of antiseptic remedies, which contain decamethoxin® (DCM). Microbicidal (Pilot Manufacturing of Institute of Organic Chemistry of National Academy of Sciences of Ukraine) and its remedies’ forms (auridexan (AU), horosten®... see more
S. Yu. Danylchenko,S. S. Kovalenko,O. G. Drushlyak,S. M. Kovalenko,L. Maes
Five novel [1,2,4]triazolo[4,3-a]quinazolin-5(4H)-one derivatives containing an amide group connected to 1 position of triazoloquinazoline moiety via sulfur-carbon or carbon chain were synthesized. The structure was confirmed by elemental analysis and 1H ... see more