Medical and Clinical Chemistry  

O. S. Lynda, L. S. Fira, P. H. Lykhatskyi

Introduction. One of the features of the development of heart diseases is the activation of lipid peroxidation processes, an increase in the number of prooxidant processes, which is a consequence of the effects on the living system of hemodynamic disorder... see more

Kh. M. Ilnytska, L. O. Datsyuk, O. Ya. Sklyarov

Introduction. The simultaneous effect of several ulcerogenic factors, different due to their mechanism of action on the mucous membranes of the digestive organs needs deep elucidation. The studies were focused on the combined effect of the low intensity X... see more

A. G. Shulgay, L. V. Tatarchuk, M. S. Hnatjuk

Introduction. Removal of large volumes of liver parenchyma is complicatedby postresection portal hypertension. The latter leads to a morphological rearrangement of the organs of the portal hepatic vein, the damage to their structures, and the growth of en... see more

I. V. Gerush, N. P. Grigorieva, Ye. O. Ferenchuk

Introduction. Kidney disease is one of the most common problems of modern medicine. The aim of the study – to determine the effect of glutathione on the change in biochemical findings of blood under conditions of experimental nephropathy.Research Methods.... see more

T. V. Usenko, V. G. Shulyak, M. G. Prodanchuk

Introduction. One of the most commonly used active substances of the triazole fungicides group is tebuconazole. Preliminary toxicological studies of peripheral blood have shown hematotoxic effect.The aimof the study– to investigate the hemopoiesis in the ... see more

?. ?. Dub, ?. ?. lishch, L. V. Vronska, I. P. Stechyshyn

Introduction. Diabetes mellitus is a social catastrophe that deprives life of millions of people and the worst trend is that two-thirds of them are employable population. The search for new hypoglycemic agents is an actual problem task of modern pharmacy,... see more

Yu. O. Sklyarova, I. S. Fomenko

Introduction. Medication-induced enteropathy plays an important part among factors leading to the development of small intestinal injury. There are some evidences indicating a potential preventive action of hydrogen sulfide (H2S) donors against drug-induc... see more

V. P. Puda, L. S. Fira, P. H. Lykhatskyi

Introduction. The problem of pharmacological correction of inflammation, is still relevant, because it is not completely solved by modern medicine. One of the promising areas for creating safe and effective anti-inflammatory drugs is phytotherapy. In rece... see more

N. H. Kopchak, O. S. Pokotylo

Introduction. The article presents new data on the age-specific features of the fatty acid composition of the total serum lipids of white male rats with experimental alimentary obesity in the comparative effect of intragastric administration of biological... see more

M. M. Korda, Ye. B. Dumukhalska, T. Ya. Yaroshenko

Introduction. Lead is a protoplasmic poison and has detrimental effects on the nervous, cardiovascular system and blood as all heavy metals. It violates enzymatic reactions, depress the immunobiological resistance of the body. Lead affects humoral immune ... see more

?. M. Musiienko, O. V. Denefil, Z. M. Nebesnaya, S. B. Kramar

Introduction. Myocardial infarction is a dynamic process accompanied by the transition of reversible changes to irreversible ischemic injury and completes the replacement of the reduced part of the myocardium by a fibrous scar.The aim of the study– to det... see more

L. A. Ponomarenko, O. A. Lykholat, ?. A. Ponomarenko

Introduction. Gastroesophageal reflux disease (GERD) and peptic ulcer (PU) of the duodenum belonging to the group of acid-dependent diseases (ADD) remain the most common among gastroenterological pathologies. The main pathogenic component of the diseases,... see more

E. A. Parashchuk, S. M. Marchyshyn, M. V. Kyryliv, I. R. Bekus

Introduction.saxifragepimpinella (Pimpinella saxifraga L.) from the family of celery (Apiaceae) has long been used in folk medicine as expectorant, diuretic, anti-inflammatory, sedative, and pain medication. It is recommended for catarrhal airways, trache... see more

V. V. Ivchuk, T. Yu. Kopteva, T. A. Kovalchuk

Introduction. Chronic obstructive pulmonary disease (COPD) of professional etiology, which is accompanied not only by changes in the respiratory tract, but also by changes in the hemostatic system takes an important place among diseases of the respiratory... see more

L. A. Boyko, L. S. Fira, N. I. Burmas

Introduction. Getting into the human body and animals, organophosphorous substances cause the activation of free radical processes, suppress protective and compensatory forces, inhibit the enzymes involved in the energy supply of cells. Tetrachloromethane... see more

O. Ye. Lyubovich, I. M. Klishch, A. S. Volska, Kh. I. Kurylo

Introduction. In the pathogenesis of many pathological conditions, the violation of the proteinase-inhibitor system is important. In the absence of proper control of proteolysis, a number of pathological conditions, accompanied by the appearance of destru... see more

O. B. Lys, M. S. Regeda

Introduction. The activation of adrenergic and hypothalamic-pituitary-adrenal systems leads to the Selye stress triad, the first component of which is argenal gland hypertrophy and increased synthesis of glucocorticoids and catecholamines. Arginine is a n... see more

O. A. Kostiuk, O. V. Denefil, T. K. Golovata

Introduction. Determining the mechanisms of damaging the influence of stress on the heart in persons with different reactivity can contribute to the development of individual methods of correction.The aim of the study – to determine the effect of immobili... see more

S. Ya. Beley, I. P. Stechyshyn, A. I. Dub

Introduction. According to recent WHO data, today the disease of the respiratory system is the leading cause of death and disability in the world. In accordance with the formular system of Ukraine (2009), the treatment of acute broncho-pulmonary diseases ... see more

Iu. M. Ordynskyi, O. V. Denefil

Introduction. Determining the mechanisms of damaging the influence of stress on the heart in persons with different reactivity can contribute to the development of individual methods of correction.The aim of the study–to determine the effect of immobiliza... see more

A. V. Rutska

Introduction. The widespread prevalence of tobacco smoking is a global problem of humanity, the solution of which is directed at the efforts of many scientists and professionals. At the same time, the distinctive feature of modern food technologies is the... see more

S. V. Nesteruk, I. M. Klishch

Introduction. Disorganization of peroxidation processes plays an important role in the pathogenesis of a mechanical nonpenetrating corneal injury [11], but these interrelationships were not been studied sufficiently, which led us to study the proper direc... see more