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22.555  Articles
1 of 2.257 pages  |  10  records  |  more records»
High throughput DNA and RNA sequencing (DNA-Seq and RNA-Seq) is increasingly impacting the clinical practice of medicine.  RNA-Seq has so far had a smaller role in the clinical practice, but it has advantageous features and is complementary to DNA-Se... see more

Uncontrolled developments of new blood vessels take place in cancer and many other life threatening diseases. Currently, RNA interference has boosted the therapeutic prospects for inhibiting gene expression responsible for increased and uncontrolled angio... see more

The introduction of a double-stranded RNA (dsRNA) into an organism to induce sequence-specific RNA interference (RNAi) of a target transcript has become a powerful technique to investigate gene function in nematodes and many organisms. Data provided here ... see more

Stress granule (SG) formation is a primary mechanism through which gene expression is rapidly modulated when the eukaryotic cell undergoes cellular stresses (including heat, oxidative, viral infection, starvation). In particular, the sequestration of spec... see more

Milk fat is a key factor affecting milk quality and is also a major trait targeted in dairy cow breeding. To determine how the synthesis and the metabolism of lipids in bovine milk is regulated at the miRNA level, primary mammary epithelial cells (pMEC) d... see more

Triple-negative breast cancer (TNBC) is an operational term for breast cancers lacking targetable estrogen receptor expression and HER2 amplifications. TNBC is, therefore, inherently heterogeneous, and is associated with worse prognosis, greater rates of ... see more

Lung cancer is the leading cause of cancer deaths worldwide, yet there remains a lack of specific and sensitive tools for early diagnosis and targeted therapies. High-throughput sequencing techniques revealed that non-coding RNAs (ncRNAs), e.g., microRNAs... see more

A transcritômica permite catalogar todas as diferentes classes de transcritos presentes nas células, possibilitando a quantificação dos níveis de expressão variáveis de cada transcrito durante o processo de desenvolvimento e sob diferentes condições fisio... see more

A transcritômica permite catalogar todas as diferentes classes de transcritos presentes nas células, possibilitando a quantificação dos níveis de expressão variáveis de cada transcrito durante o processo de desenvolvimento e sob diferentes condições fisio... see more

1 of 2.257 pages  |  10  records  |  more records»