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68.512  Articles
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Copanlisib is a pan phosphatidylinositol 3-kinase (PI3K) inhibitor approved for follicular lymphoma. In this paper, we present the data of development and validation of a high-performance liquid chromatography (HPLC) method for the quantitation of copanli... see more

A simple, selective and rapid LC-ESI-MS/MS method has been developed and validated for the quantification of ivosidenib in mice plasma using warfarin as an internal standard (I.S.) as per regulatory guideline. Sample preparation was accomplished through a... see more

A simple, sensitive and rapid assay method has been developed and validated for the estimation of enzalutamide, N-desmethylenzalutamide (active metabolite of enzalutamide), darolutamide and ORM-15341 (active metabolite of darolutamide) on mice dried blood... see more

Naringin (CAS no: 10236-47-2) is a flavonone glycoside obtained from Citrus paradisi (grapefruit), a natural bioenhancer and reported to enhance the bioavailability of drugs by inhibiting cytochrome P450 and P-glycoprotein (P-gp). The aim of the present s... see more

Nowadays, electronic throttle control system is widely adapted in the motorcycle for better drivability, fuel economy and reduces the emissions. In such systems, pedal follower or torque based approach are used for calculating the required throttle angle ... see more


Ulixertinib (BVD-523) is a novel and selective reversible inhibitor of ERK1/ERK2. In xenograft studies it inhibited tumor growth in BRAF-mutant melanoma and colorectal xenografts as well as KRAS-mutant colorectal and pancreatic models. Ulixertinib is curr... see more

MODERN STATE OF CREATION, PRODUCTION AND RESEARCH OF DRUGSI.V. Kozak, M.B. Demchuk, T.A. HroshovyiI.HorbachevskyTernopilStateMedicalUniversityIntroduction. Creating new systems and drug delivery aimed at increasing the effectiveness and safety of treatmen... see more

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