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10.243  Articles
1 of 1.025 pages  |  10  records  |  more records»
The European Organization for Research and Treatment of Cancer/National Cancer Institute of Canada Phase III trial has validated as a current regimen for high-grade gliomas (HGG) a maximal safe surgical resection followed by radiotherapy with concurrent t... see more

Heat shock proteins (HSPs) are molecular chaperones and one of the cell’s most important regulatory proteins present in all species. HSPs are a multigene family classified into six families according to their molecular weight range between 8KDa to 110KDa:... see more

Molecular genetics coupled with advances in immunology and parasite culture has become a powerful tool to study animal parasites and their vectors. Recombinant DNA techniques allow one to identify individual genes of DNA probes, amplify the nucleic acid o... see more

Heat Shock Protein (HSP) is a molecular chaperone that prevents stress-induced aggregation of partially denatured proteins and promotes their return to native confirmation when the condition is favorable. As molecular chaperones, the HSP protect protein s... see more

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In the mid 1950's the Nobel Prize Laureate Christian B. Anfinsen from his research on the folding of ribonuclease A, began to concentrate on the problem of the relationship between structure and function in enzymes. On the basis of studies on ribonuclease... see more

Ulcerative colitis (UC) is a form of inflammatory bowel disease (IBD) characterized by damage of large bowel mucosa and frequent extra-intestinal autoimmune comorbidities. The role played in IBD pathogenesis by molecular chaperones known to interact with ... see more

Molecular genetics coupled with advances in immunology and parasite culture has become a powerful tool to study animal parasites and their vectors. Recombinant DNA techniques allow one to identify individual genes of DNA probes, amplify the nucleic acid o... see more

Gaucher’s disease (GD) is the most frequently inherited lysosomal storage disease, presenting both visceral and neurologic symptoms. Mutations in acid ß-glucocerebrosidase disrupt the sphingolipid catabolic pathway promoting glucosylceramide (GlcCer) accu... see more

1 of 1.025 pages  |  10  records  |  more records»