21 articles in this issue
Dr.Pravina B. Piste
In the designing and synthesis of new heterocyclic compounds, containing two different pharmacophores, we have carried out new series of 3-(4-chlorophenyl)-4-methylidene-4,8-dihydro-2H,5H-1,3-thiazino[5,4-e]-1,3-oxazine-2,5,7(3H)-trione derivatives (5a-5k... see more
Y Bindu Vani,C. Surya Prakash Reddy
The present work is concerned with the formulation and evaluation of Piroxicam emulgel employing carbopol 934 and xanthan gum as polymers. The emulgel is prepared by combining the gel and emulsion. The gel in formulations were prepared by dispersing Carbo... see more
E. Vadivel,Poorva P. Dabholkar
From the last few decades the importance of search for natural polymer as pharmaceutical excipients has been increasing due to their various advantages. Natural polymer has been used in different pharmaceutical formulations. They are easily available, non... see more
V Deepa,S Sreekumar
To validate the efficacy of viper anti-venom activity, a total of 79 phytochemicals from Phyllanthus emblica and 59 phytochemicals from Tamarindus indica were docked against each of the nine selected viper venom proteins such as basic phospholipase A2 VRV... see more
Amoolya Chennuri,D. Prasanthi
Self-emulsifying drug delivery systems are a promising aptemsproach for the formulation of drug compounds with poor aqueous solubility. The main objective of this work was to formulate liquid and solid-self emulsifying drug delivery systems for poorly sol... see more
Ravi Shekhar,P. Sharma
A new approach to zero- order drug delivery that includes geometric factors is described. Systems such asmultilayered tablets and other geometrically altered devices have been created to perform this function. Themulti-layered matrix system overcomes inhe... see more
C. Soujanya,P.Ravi Prakash
The objectives of the present study were to define effects on the hypercholesterolemia activityand pharmacokinetics of a novel transdermal proniosomal gel incorporating Lovastatin prepared bycoacervation phase separation method. On the basis of the prelim... see more
G. Muralichand,D. V. R. N. Bhikshapathi
The objective of this study was to develop solid dispersions of Nifedipine which has low aqueous solubility and bioavailability. Preliminary solubility studies were carried out using various hydrophilic polymers. The formulations were then optimized and e... see more
Narendra G. Patre,s. S. Patil
A simple and sensitive, HPTLC method has been developed for the quantitative estimation of felodipine in it’s single component tablet formulation. The separation was carried out on Merck aluminium plates precoated with silica Gel 60 F254 using n -hexane: ... see more
Prudence A Rodrigues,P R Murugesan,Anjana Balakrishnan,Megha Binoy,Jithin Titus Jacob1
The objective of the present study is to analyse the effectiveness of carvedilol and metoprolol in the management of atrial fibrillation in post operative coronary artery bypass graft surgery patients. Atrial fibrillation occurs frequently soon after coro... see more
Shashank Shekhar Mishra,Neeraj Kumar,Hamendra Pratap Singh,Shashi Ranjan,Chandra Shekhar Sharma
Asthma is a disease affecting the airways that carry air to and from lungs. Exposure to various irritants and substances that trigger allergies (allergens) can trigger signs and symptoms of asthma. The prevalence of asthma varies widely in different regio... see more
Edcy Edvi,Angel Rose,Jose Celesti Sibi,Elsa Sandra Thomas,P A Sreeja
Medication Appropriate Index (MAI) is used to assess the quality of antibiotic prescribing. The aim of the study to determine the risk factors of obstructive airway disease and to assess the appropriateness of ongoing antibiotic therapy using medication a... see more
J. A. Melo1,K. M. M. Aroucha1,L. P. M. Santos,C. M. Moraes,J A. Takahashi,A. C. Oliveira,T. M Condé,F. C Nascimento
Popularly known as red mandioqueira, ‘mandioqueira vermelha’, Qualea paraensis Ducke is a plant species belonging to the family Vochysiaceae, with a natural distribution in the Amazon region. It is used in traditional medicine, by native communities of th... see more
Garima Shrivastava,Manjul Shrivastava
New Schiff base (2-[(1H-benzimidazol-2-ylimino) methyl]-4,6- diiodophenol) was synthesized by the condensation of aryl/hetero aromatic aldehyde (3,5diiodosalicylaldehyde) with 2- amino benzimidazole under conventional and microwave conditions and characte... see more
E.Damasceno Junior,J. M. F. DE Almeida,I. N. Silva,M. S. B. Silva,N. S. Fernandes
In vitro dissolution tests are an extremely important tool in the development and quality control of drugs, making it possible to evaluate the performance or efficiency of the pharmaceutical form in releasing the active substance through the amount dissol... see more
Marcos Reynoso,María E. Balderrama Coca,Ivana Y. Brodkiewicz,,Gloria Jaime,,Marina Perotti,Carola Schuff,Nancy R Vera
The chemical machinery of vegetables offers a great diversity of biological properties and plays a fundamental role in the field of pharmacology. The search for new drugs with fewer adverse effects represents a challenge for researchers. The objective of ... see more
P. Srinivasa Rao,T. Rama Mohan Reddy
The current investigation was aimed with the objective of formulating Selegiline fast dissolving oral thin films allowing fast reproducible drug dissolution in oral cavity thus bypassing the first pass metabolism to enhance the patient convenience and com... see more
A. Laxmi Raj,Y. Shravan Kumar
Nebivolol is a pharmaceutical drug used for the treatment of Hypertension. It is characterized with poor solubility which limits its absorption and dissolution rate which delays onset of action. In the present study, fifteen formulations of solid dispersi... see more
P. Vamsee Kumar,Y. Shravan Kumar
In current investigation an attempt has been made to formulate and evaluate Quinapril mouth dissolving films using HPMC 50cps, E5, E15 and in combination of Pullulan by Solvent evaporation method. Sodium starch glycolate acts as a super disintegrating age... see more
Kota Ravi Kumar,Gande Suresh
The present study was designed to formulate and evaluate the Olmesartan sodium alginate microspheres. Fourteen formulations batches of microspheres (S1-S14) were prepared by using ionotropic gelation method. Sodium alginate, calcium chloride, ethyl cellul... see more
Rangu Nirmala,Gande Suresh
The purpose of this investigation was to design and develop trilayer matrix tablets of Nelfinavir prepared bydirect compression method and consisted of middle active layer with different grades of hydroxypropylmethylcellulose (HPMC), PVK K 30 and MCC. Bar... see more