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32  Articles
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Objetivo: El objetivo del presente estudio fue desarrollar y optimizar la auto-nanoemulsión forma de dosificación sólida (SNESDF) de la Lovastatina para aumentar su solubilidad. Lovastatina (cuya solubilidad en agua es 0,4 x 10-3 mg / ml) se considera que... see more

Objetivo: El objetivo del presente estudio fue desarrollar y optimizar la auto-nanoemulsión forma de dosificación sólida (SNESDF) de la Lovastatina para aumentar su solubilidad. Lovastatina (cuya solubilidad en agua es 0,4 x 10-3 mg / ml) se considera que... see more

In the present investigation, self-nanoemulsifying drug delivery system (SNEDDS), of Lovastatin is being formulated to increase the solubility and bioavailability. The optimized Lovastatin SNEDDS formulation (F8) has a composition of Acrysol EL 135 as oil... see more

The objectives of the present study were to define effects on the hypercholesterolemia activityand pharmacokinetics of a novel transdermal proniosomal gel incorporating Lovastatin prepared bycoacervation phase separation method. On the basis of the prelim... see more

Pathological formation of bone in non-skeletal soft tissues or heterotopic ossification (HO), for which there is currently no effective treatment, is considered to be mediated by activation of Hedgehog (Hh) signaling pathway. Moreover, the biochemical mec... see more

Lovastatin is a drug belonging to statins group that is used to decrease the cholesterol levels in blood. The action mechanism of lovastatin is inhibition of the activity of HMG-CoA reductase enzyme, hence reducing cholesterol production in the liver... see more

Kualitas bekasam dapat ditingkatkan dengan menggunakan starter bakteri asam laktat (BAL) untuk mengontrol proses fermentasi. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan starter Lactobacillus acidophilus pada proses fermentasi bekasam ter... see more

BACKGROUND: Atherosclerosis, which is a result of gradual deposition of lipids in the lower part of blood vessel endothelium, is the leading cause of mortality and morbidity around the world. It has been proved that some inflammatory blood markers such as... see more

Red yeast rice (RYR), produced by the fermentation of the Monascus purpureus mold, has been used for a long time in Asian cuisine and traditional medicine. It consists of multiple bioactive substances, including monacolins, which potentially can be used a... see more

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