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133  Articles
1 of 14 pages  |  10  records  |  more records»
The research focuses on the development of multiparticulate delivery system for acid-labile Lansoprazole to prevent its degradation in the acidic environment of the stomach and enhance its bioavailability via intestinal absorption. This problem can be sol... see more

Recently, lot of emphasis is being laid on oral controlled release multiple unit particulate (MUP) dosage forms, for their significant and potential benefits.  Ketorolac tromethamine (KTM) is a potent non-narcotic analgesic and anti-inflamatory drug ... see more

Gastro retentive dosage forms have potential for use as controlled-release drug delivery systems. Multiple unit systems avoid the “all-or-none gastric” emptying nature of single-unit systems. A controlled release system designed to increase its residence ... see more

5-Fluorouracil though recommended as a chemotherapeutic agent for colorectal cancer, suffers from severe systemic toxicity and so needs site-specific delivery. Objective of present investigation is to design slow release enteric coated solid formulations ... see more

The objective of the current work was to design an injectable, sustained release formulation of a combination of anticancer drugs, carboplatin and paclitaxel, for localized delivery. In this combination formulation, carboplatin was encapsulated into poly(... see more

The aim of this study was to formulate and characterize gentamicin-loaded albumin microspheres for their potential therapeutic use in E. coli K88 infections. Based on in vitro assays, it is proposed that microspheres may serve as a carrier of gentamicin a... see more

The objective of this work was to formulate and evaluate a controlled-release Oxypentifylline microspheres that fulfill the requirements for extended release medications using Ammonio Methacrylate Copolymer RS100 as polymeric material. The microsphere wer... see more

The aim of present study is to develop biodegradable microspheres of Tinidazole. Bovine Serum Albumin was used for the preparation of microspheres. They were made in four batches. The emulsion cross-linking method was used for the preparation. The quantit... see more

The recent advances in controlled delivery systems for protein pharmaceuticals such as microspheres, liposomes, pumps and implants, have provided a new avenue for delivery of vaccine antigens. Adjuvants aimed at increasing the immunogenicity of recombinan... see more

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