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42  Articles
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Objective: To investigate the efficacy of metoprolol combined with torasemide in elderly patients with degenerative valvular heart disease (DVHD) and heart failure and its influence on N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations.M... see more

Background. Analytical method is increasingly implemented into fundamental pharmaceutical chemistry and analysis, considering their high sensitivity, accuracy, specificity and expressiveness.Objective. Metoprolol’s analytical method development was the re... see more

Objetivos: El objetivo principal del presente estudio es el de facilitar la administración intranasal de tartrato de metoprolol (cardioselectivo ß1-bloqueante), mediante la formulación de microesferas mucoadhesivas.Métodos: Las microesferas se prepar... see more

The aim of the present investigation was to prepare bilayer floating tablets of metoprolol tartrate using the combination of superdisintigrants, HPMC K grade polymers and natural polymers like xanthan gum and guar gum by direct compression method. Bilayer... see more

Objetivos: El objetivo principal del presente estudio es el de facilitar la administración intranasal de tartrato de metoprolol (cardioselectivo ß1-bloqueante), mediante la formulación de microesferas mucoadhesivas.Métodos: Las microesferas se prepar... see more

In the present study we have synthesized ester prodrugs (Pa-i) of Metoprolol (I) by using pthalic anhydride and derivatives of succinic and maleic anhydride. Different codrugs (COa-i) were synthesized from prodrugs of metoprolol. All the codrugs were char... see more

This research work was carried out to determine whether the film coating is effective to prevent the photolytic degradation of Metoprolol tartrate which is known to have photosensitivity. For this purpose, two randomly selected brands of two different pha... see more

The objective is to prepare extended release micro-pellets of the s-Metoprolol Succinate which is chirally pure molecules. Commercially Metoprolol Succinate is available the racemic mixture of the s and r isomers. Out of both the isomers s-isomer is predo... see more

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