26 articles in this issue
Akiko Mizuno, Maria Ly and Howard J. Aizenstein
Subjective Cognitive Decline (SCD) is possibly one of the earliest detectable signs of dementia, but we do not know which mental processes lead to elevated concern. In this narrative review, we will summarize the previous literature on the biomarkers and ... see more
César Payán-Gómez, Diego Rodríguez, Diana Amador-Muñoz and Sandra Ramírez-Clavijo
The prefrontal cortex (PFC) is one of the brain regions with more prominent changes in human aging. The molecular processes related to the cognitive decline and mood changes during aging are not completely understood. To improve our knowledge, we integrat... see more
Ryan Thompson and Christina Chan
The Neuron Restrictive Silencer Factor (NRSF) is the well-known master transcriptional repressor of the neuronal phenotype. Research to date has shown that it is an important player in the growth and development of the nervous system. Its role in the matu... see more
Hunter J. Fassett, Claudia V. Turco, Jenin El-Sayes and Aimee J. Nelson
(1) Background: The primary motor cortex (M1) experiences reorganization following spinal cord injury (SCI). However, there is a paucity of research comparing bilateral M1 organization in SCI and questions remain to be answered. We explored the presence o... see more
Craig A. Erickson, Walter E. Kaufmann, Dejan B. Budimirovic, Ave Lachiewicz, Barbara Haas-Givler, Robert M. Miller, Jayne Dixon Weber, Leonard Abbeduto, David Hessl, Randi J. Hagerman and Elizabeth Berry-Kravis
Preclinical studies using animal models of fragile X syndrome have yielded several agents that rescue a wide variety of phenotypes. However, translation of these treatments to humans with the disorder has not yet been successful, shedding light on a varie... see more
Yi Zhou and Brian D. Greenwald
Sleep disturbance after traumatic brain injury (TBI) has received growing interest in recent years, garnering many publications. Insomnia is highly prevalent within the mild traumatic brain injury (mTBI) population and is a subtle, frequently persistent c... see more
Julio-César García and Rosa-Helena Bustos
Genetics has led to a new focus regarding approaches to the most prevalent diseases today. Ascertaining the molecular secrets of neurodegenerative diseases will lead to developing drugs that will change natural history, thereby affecting the quality of li... see more
Fabrizio Schifano
Over the last decade, the emergence of a vast range of new/novel/emerging psychoactive substances (NPS) has progressively changed drug market scenarios, which have shifted from the ‘street’ to a ‘virtual’/online environment. [...]
Luis Miguel Dos Santos
The researcher employed personal belief system (PBS) theory as the theoretical foundation for this study because it holds that teachers’ PBSs may influence their teaching behaviours, teaching styles, and pedagogies in classroom practice due to cultu... see more
Mayra Gutiérrez-Muñoz, Martha E. Fajardo-Araujo, Erika G. González-Pérez, Victor E. Aguirre-Arzola and Silvia Solís-Ortiz
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Adam C. Lieber, Estee Hong, David Putrino, Dominic A. Nistal, Jonathan S. Pan and Christopher P. Kellner
While significant research has been performed regarding the use of thrombolytic agents and thrombectomy in the setting of acute stroke, other factors, such as nutritional status of stroke patients, is a less explored topic. The topic of nutrition is criti... see more
Jorge Flores-Hernández, Jeanette A. Garzón-Vázquez, Gustavo Hernández-Carballo, Elizabeth Nieto-Mendoza, Evelyn A. Ruíz-Luna and Elizabeth Hernández-Echeagaray
Huntington’s Disease (HD) is a degenerative disease which produces cognitive and motor disturbances. Treatment with GABAergic agonists improves the behavior and activity of mitochondrial complexes in rodents treated with 3-nitropropionic acid to mim... see more
Cynthia Bean, Shauna-Kay Spencer, Mallikarjuna R. Pabbidi, Jamie Szczepanski, Sarah Araji, Sellena Dixon and Kedra Wallace
Using an animal model of hemolysis elevated liver enzymes low platelets (HELLP) that has systemic inflammation and neuroinflammation we wanted to determine if blood brain barrier (BBB) permeability, cerebral edema, vascular tone, and occludin expression w... see more
Ahmad Almahozi, Maan Alsaaid, Saeed Bin Jabal and Amer Kamal
The selective retrieval of some information may lead to the forgetting of related, but non-retrieved information. This memory phenomenon is termed retrieval-induced forgetting (RIF). Active inhibition is thought to function to resolve interference from co... see more
Anna W. Lee, Pamela Ventola, Dejan Budimirovic, Elizabeth Berry-Kravis and Jeannie Visootsak
George Deraos, Eftichia Kritsi, Minos-Timotheos Matsoukas, Konstantina Christopoulou, Hubert Kalbacher, Panagiotis Zoumpoulakis, Vasso Apostolopoulos and John Matsoukas
Background: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system. MS is a T cell-mediated disease characterized by the proliferation, infiltration, and attack of the myelin sheath by immune cells. Previous studies have shown tha... see more
Darija Šoltic, Melissa Bowerman, Joanne Stock, Hannah K. Shorrock, Thomas H. Gillingwater and Heidi R. Fuller
Unravelling the complex molecular pathways responsible for motor neuron degeneration in amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) remains a persistent challenge. Interest is growing in the potential molecular similarities betwe... see more
Dorina Cadar, Marius Usher and Eddy J. Davelaar
Although ageing is known to affect memory, the precise nature of its effect on retrieval and encoding processes is not well understood. Here, we examine the effect of ageing on the free recall of word lists, in which the semantic structure of word sequenc... see more
Tess S. Fotidzis, Heechun Moon, Jessica R. Steele and Cyrille L. Magne
Recent evidence suggests the existence of shared neural resources for rhythm processing in language and music. Such overlaps could be the basis of the facilitating effect of regular musical rhythm on spoken word processing previously reported for typical ... see more
Linnea Wilder, Kari L. Hanson, Caroline H. Lew, Ursula Bellugi and Katerina Semendeferi
Williams Syndrome (WS) is a neurodevelopmental disorder caused by a deletion of 25–28 genes on chromosome 7 and characterized by a specific behavioral phenotype, which includes hypersociability and anxiety. Here, we examined the density of neurons a... see more
Yoshio Takashima, Joyee Tseng, McKenzie J. Fannon, Dvijen C. Purohit, Leon W. Quach, Michael J. Terranova, Khush M. Kharidia, Robert J. Oliver and Chitra D. Mandyam
The present study examined differences in operant responses in adult male and female rats during distinct phases of addiction. Males and females demonstrated escalation in methamphetamine (0.05 mg/kg, i.v.) intake with females showing enhanced latency to ... see more
Emil N. Coman, Helen Z. Wu and Shervin Assari
Poor comparability of social groups is one of the major methodological problems that threatens the validity of health disparities (HD) research findings. We illustrate a methodological solution that can additionally unpack the mechanisms behind differenti... see more
Brenda Hanna-Pladdy, Hyun Choi, Brian Herman and Spenser Haffey
Ines A. Basten, Richard Boada, Hudson G. Taylor, Katherine Koenig, Veridiana L. Barrionuevo, Ana C. Brandão and Alberto C. S. Costa
Down syndrome (DS) is the most common genetically-defined cause of intellectual disability. Neurodevelopmental deficits displayed by individuals with DS are generally global, however, disproportionate deficits in cognitive processes that depend heavily on... see more
Charles S. H. Robinson, Natalie B. Bryant, Joshua W. Maxwell, Aaron P. Jones, Bradley Robert, Melanie Lamphere, Angela Combs, Hussein M. Al Azzawi, Benjamin C. Gibson, Joseph L. Sanguinetti, Nicholas A. Ketz, Praveen K. Pilly and Vincent P. Clark
Background: Poor sleep quality is a common complaint, affecting over one third of people in the United States. While sleep quality is thought to be related to slow-wave sleep (SWS), there has been little investigation to address whether modulating slow-wa... see more
Richard E. Kast, Nicolas Skuli, Iacopo Sardi, Felix Capanni, Martin Hessling, Guido Frosina, Anton P. Kast, Georg Karpel-Massler and Marc-Eric Halatsch
The CAALA (Complex Augmentation of ALA) regimen was developed with the goal of redressing some of the weaknesses of 5-aminolevulinic acid (5-ALA) use in glioblastoma treatment as it now stands. 5-ALA is approved for use prior to glioblastoma surgery to be... see more