10 articles in this issue
Anna Meiliana,Andi Wijaya
BACKGROUND: Many chronic disorders, including vascular diseases, metabolic syndrome, and neurological diseases, are known to share a common factor of excessive inflammation. It takes a lot of energy to heal damaged tissue, which is a complicated process. ... see more
Emilia Vivi Arsita,Dwi Aris Agung Nugrahaningsih,Ahmad Hamim Sadewa
BACKGROUND: Glutathione S-transferase Mu-1 (GSTM1) is known to undergo polymorphism and plays role in drug metabolism including Paclitaxel (PTX), the first-line chemotherapy for breast cancer. However, the effect of GSTM1 polymorphism against chemotherapy... see more
Aden Arrafif Bahtiarsyah,Lisna Hidayati,Nastiti Wijayanti,Tri Rini Nuringtyas
BACKGROUND: Type 2 diabetes mellitus affects glucose metabolism resulting in hyperglycemia. The bark of Cinnamomum burmannii (CB) and the leaves of Aquilaria malaccensis (AM) are believed to be effective for diabetes treatment. This study evaluated the sy... see more
Moordiani Moordiani,Dhania Novitasari,Ratna Asmah Susidarti,Muthi' Ikawati,Jun-ya Kato,Edy Meiyanto
BACKGROUND: Liver cancer is the third leading mortality in cancer. Curcumin shows effective anticancer potency against various cancer including liver cancer. The synthesized curcumin analog compounds Pentagamavunone-1 (PGV-1) and Chemoprevention Curcumin ... see more
Ahmad Syauqy Tafrihani,Nisa Ul Hasanah,Dhiya Ulhaq Salsabila,Ratih Kurnia Wardani,Ummi Maryam Zulfin,Muthi' Ikawati,Edy Meiyanto,Riris Istighfari Jenie
BACKGROUND: Cardamom (Amomum cardamom) essential oil (CEO) contains monoterpenes with antioxidant activity and is reported to exhibit anticancer activity against some cancer cell lines. Triple-negative breast cancer (TNBC) has the lowest prognosis among b... see more
Ni Putu Sukma Sumantri Prabandari,Ni Kadek Mulyantari,Made Sukmawati,Anak Agung Ngurah Subawa,I Wayan Gede Artawan Eka Putra,Anak Agung Wiradewi Lestari,I Nyoman Wande,Ni Nyoman Mahartini
BACKGROUND: Early-onset neonatal sepsis (EONS) is an acute infection and sepsis occurring within the first 24 hours of new-born life. An increase in procalcitonin levels, presepsin levels, and neutrophil-to-lymphocyte ratio (NLR) in EONS subjects have bee... see more
Ratu Purwanti,Agnes Rengga Indrati,Nida Suraya,Maya Marinda Montain,Ines Atmosukarto,Neni Nurainy,Ida Parwati
BACKGROUND: BCG vaccine has been proven to be effective protection against tuberculosis (TB) meningitis and miliary TB. However, for protection against pulmonary TB, the results remains vary widely. Recombinant vaccine consisting of two immunodominant Mtb... see more
Sonar Soni Panigoro,Sinta Chaira Maulanisa,Ahmad Kurnia,Denni Joko Purwanto,Primariadewi Rustamadji,Herqutanto Herqutanto,Ferry Sandra
BACKGROUND: Chemotherapy has reported to stimulate immune system through direct activation of cluster of differentiation (CD)8+ T cells. Neoadjuvant chemotherapy (NAC) is known to improve the clinical response of locally advanced breast cancer (LABC) pati... see more
Anastasia Armimi,Afina Firdaus Syuaib,Katherine Vanya,Marselina Irasonia Tan,Dessy Natalia,David Virya Chen,Chikako Ono,Yoshiharu Matsuura,Anita Artarini,Ernawati Arifin Giri-Rachman
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects humans' lower respiratory tracts and causes coronavirus disease-2019 (COVID-19). Neutralizing antibodies is one of the adaptive immune system responses that can reduce SARS-C... see more
Syanindita Puspa Wardhani,Khilmi Ainun Nadliroh,Al Mazida Fauzil Aishaqeena,Fahriza Abid Sonia,Achmad Guntur Hermawan Suryo Adji,Intan Masyfufah Hanim,Rizkia Milladina Hidayatulloh,Anna Fuji Rahimah,Ardian Rizal,Peter Sugita,Ferry Sandra,Djanggan Sargowo
BACKGROUND: Cardiometabolic syndrome is a risk factor for the development of diseases related to cardiovascular disease and decreased renal function. Ganoderma lucidum polysaccharide peptide (GLPP) has been reported to have anti-inflammatory and antioxida... see more