13 articles in this issue
Yudi Her Oktaviono,Suryo Ardi Hutomo,Kevin Luke
BACKGROUND: Coronary artery disease (CAD) remains as the world number one cause of morbidity and mortality. Endothelial progenitor cells (EPCs) are known to be involved in vascular biology. Current review briefly summarizes the basics of EPCs and its clin... see more
Anna Meiliana,Nurrani Mustika Dewi,Andi Wijaya
BACKGROUND: A lot of contemporary cancer research has concentrated on genetic influence. However, cancer also involves biochemical changes, such as metabolic adaptation to support the aberrant cell proliferation.CONTENT: The fast cell proliferation in can... see more
Desy Thayyil Menambath,Durga Rao Yella,Ashok Prabhu Khandige,Sudha Kuthethur,Nandini Mangalore
BACKGROUND: Diabetes mellitus is a common disease worldwide which affects renal function. Cardiovascular morbidity and mortality in diabetes patients can be accelerated by dyslipidemia. Small dense lowdensity lipoprotein-cholesterol (sdLDL-C) is atherogen... see more
Erna Susanti,Endang Susilowati
BACKGROUND: Signaling pathways contributing to cholesterol efflux and inhibitory inflammation in atherosclerosis that has not been explored is the liver X receptor (LXR). Catechin as LXR agonist influences the expression of Niemann-pick C1 like 1 (NPC1L1)... see more
Yanuarita Tursinawati,Arum Kartikadewi,Ari Yuniastuti,R Susanti
BACKGROUND: One of the hormones that plays a role in glucose metabolism of Type 2 Diabetes Mellitus (T2DM) is melatonin. Its genetic variation is believed to play a significant role in the pathophysiology of obese and non-obese T2DM. The role of MTNR1B (m... see more
Astuti Giantini,Ina Susianti Timan,Erlin Listiyaningsih,Rahajuningsih Dharma,Rianto Setiabudy,Idrus Alwi,Lia Gardenia Partakusuma,Nuri Dyah Indrasari,Alida Roswita Harahap,Siskawati Suparmin,Windy Sahar,Renan Sukmawan
BACKGROUND: Light transmission aggregometry (LTA) and VerifyNow is commonly used to measure platelet responsiveness to clopidogrel. This study aimed to compare the results of LTA and VerifyNow P2Y12 assay for assessing the clopidogrel resistance in patien... see more
Ronald Winardi Kartika,Idrus Alwi,Franciscus Dhyanagiri Suyatna,Em Yunir,Sarwono Waspadji,Suzanna Immanuel,Todung Silalahi,Saleha Sungkar,Jusuf Rachmat,Saptawati Bardosono,Mirta Hediyati Reksodiputro
BACKGROUND: Diabetic foot ulcer (DFU) is the most common and threatening complication of Diabetes Mellitus (DM). Ideal wound dressing for DFU management should relieve symptoms, provide wound protection, and encourage healing. Advanced-Platelet Rich Fibri... see more
Mahmood Thamer Altemimi,Alaa Khattar Musa,Abbas Ali Mansour
BACKGROUND: Obese women with polycystic ovary syndrome (PCOS) are at high risk for developing type 2 diabetes mellitus (T2DM). A baseline oral glucose tolerance test (2-h OGTT) is important to screen for dysglycemia in PCOS particularly those high risk wo... see more
Frisma Sagara Brilliyanto,Gatut Suhendro,Indri Wahyuni,Maftucah Rochmanti,Windhu Pramono
BACKGROUND: Posterior capsule opacification (PCO) often occurs after cataract surgery. Metformin has been known to have an ability to inhibit fibrosis. This study aimed to investigate the effects of metformin on cell contractility, collagen deposition and... see more
Anggi Laksmita Dewi,Dewi Kartikawati Paramita,Jajah Fachiroh
BACKGROUND: Single nucleotide variations (SNV) have been mapped to be associated with several human conditions and diseases. To validate the association between SNV to certain human traits or diseases, a large number of subjects must be included. Thus, in... see more
Yenny Kandarini,Gede Wira Mahadita,Sianny Herawati,Anak Agung Wiradewi Lestari,Ketut Suega,I Gde Raka Widiana
BACKGROUND: Monitoring of iron status in chronic kidney disease patients is important, however inflammation may hinder its monitoring. Soluble transferrin receptor (sTfR) is an alternative parameter to overcome this issue, whereas ferritin play a part in ... see more
Dwi Wahyuni,Joko Waluyo,Jekti Prihatin,Fersty Isna Kusumawardani,Aditya Kurniawan
BACKGROUND: Traditional medicine that might be useful to treat typhoid fever is earthworms (Pheretima javanica K.). It is important to know whether any substances contained in Pheretima javanica K. extract are toxic and have pharmacological effects, which... see more
Yessy Ariesanti,Ferry Sandra,Bianda Claresta,Livia Alvita
BACKGROUND: Wound healing is an essential biological process that consists of sequential steps aimed at restoring the architecture and function of damaged cells and tissues. There are empirical evidences of using pure coffee bean powder as an alternative ... see more