8 articles in this issue
Anna Meiliana,Andi Wijaya
BACKGROUND: The discovery of endothelial progenitor cell (EPC) a decade ago by Asahara, et al has refuted the previous belief that vasculogenesis only occurs during embryogenesis. The reduced circulating concentration of EPCs is a surrogate marker of endo... see more
Anna Meiliana,Ilhamjaya Patellongi,Andi Wijaya
BACKGROUND: Many previous studies have reported that central obesity is related to inflammation and endothelial dysfunction. It has also been reported that resistin can induce proinflammatory cytokines TNF-a and IL-6, which can result in endothelial dysfu... see more
Yani Lina,Gatot Susilo Lawrence,Andi Wijaya
BACKGROUND: The prevalence of obesity has increased dramatically in recent years. It is commonly associated with type 2 diabetes, coronary artery disease, and hypertension. White adipose tissue (WAT) is a major site of energy storage and is important for ... see more
Ellis Susanti,Marsetio Donosepoetro,Gatot Susilo Lawrence
BACKGROUND: Patients with Diabetes Melitus are proven to be prone to atherosclerosis and coronary heart disease, especially type 2 Diabetes Melitus (T2DM) patient who have higher risk and mortality for cardiovascular risk factor. The Dyslipidemia conditio... see more
Mona Yolanda,Marsetio Donosepoetro,Anwar Santoso
BACKGROUNDS: Heart failure, a new epidemic of cardiovascular disease, has become an important issue and its prognosis is poor. Heart failure is the condition where the impaired heart cannot pump enough blood to provide the needs of metabolic tissues and o... see more
Marissa Arifin,Marsetio Donosepoetro,Sutomo Kasiman
BACKGROUND: Recent clinical studies have suggested that ?-glutamyltransferase (?-GT) can trigger oxidative stress within the plaque. This study aimed to investigate whether serum ?-GT might be as a risk factor of coronary heart disease (CHD), and measure ... see more
Tommy Heryantho,Andi Wijaya,Teguh Santoso
BACKGROUND: Thrombus is a main cause of cardiac death. Therefore identifying which coronary artery plaque is vulnerable to rupture is a critical step for cardiac intervention to prevent future cardiac events. Systemic biochemical markers are used for pred... see more
Tetty Hendrawati,Syakib Bakri,Mansyur Arif
BACKGROUND: Asymmetric dimethylarginine (ADMA) is a competitive inhibitor of nitric oxide synthase (NOS). ADMA reduces NO synthesis when its concentration elevates. ADMA is a novel risk factor for cardiovascular disease. Plasma ADMA accumulates in patient... see more