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17.069  Articles
1 of 1.708 pages  |  10  records  |  more records»
Objectives: Accurately identifying the cellular, biomolecular, and toxicological functions of anticancer drugs help to decipher the potential risk of genotoxicity and other side effects. Here, we examined bleomycin for cellular, molecular and toxicologica... see more

 
The aim of the current study was to determine the mutagenic effect and DNA damage of Malaysian white Portland cement (MWPC) and White mineral trioxide aggregate (WMTA) using Ames test and Comet assay. The cytotoxicity of WMTA and MWPC was evaluated using ... see more

Micronuclei are small, aberrant nuclear compartments containing mis-segregated chromosomes or chromosomal fragments. During telophase, dysfunctional micronuclear envelope reassembly leaves the micronuclear envelope highly unstable and rupture-prone. Follo... see more

This study was aimed to evaluate DNA fragmentation by using Comet assay in naturally infected sheep with Anaplasmosis before and after treatment with the Comet method, which shows DNA damage specifically. In the study, blood samples were collected from 10... see more

The alkaline single cell gel electrophoresis technique (SCGE), also known as the comet assay, is an evaluation method for estimating DNA damage and genotoxicity. This assay is used to measure DNA single-strand breaks, alkali-labile sites and DNA cross-lin... see more

Heavy metals affect plant system in various toxic ways including morphophysiologicalalterations and genotoxic damages inside a plant cell. The extentof DNA damage under any genotoxic agents can be effectively measured in singlecells applying comet assay a... see more

Breast cancer is the second leading cause of cancer deaths in women. Several drugs including cisplatin and carboplatin have shown tremendous effectivity in reducing cancer; however development of drug resistance by breast cancer cells to overcome cytotoxi... see more

Ionizing radiation (IR) presents a risk to human health via DNA damage even when administered at low doses, such as those used in panoramic radiography. Objectives: This study used the comet assay to assess DNA damage in buccal mucosa cells consequent to ... see more

Eugenol and its isomer isoeugenol are both used as flavouring agents or food additives in food products, and have both some similar biological properties. However, the difference in biological activities between eugenol and isoeugenol is rarely studied. I... see more

1 of 1.708 pages  |  10  records  |  more records»