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68  Articles
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Micronuclei are small, aberrant nuclear compartments containing mis-segregated chromosomes or chromosomal fragments. During telophase, dysfunctional micronuclear envelope reassembly leaves the micronuclear envelope highly unstable and rupture-prone. Follo... see more

Individual responses to radiotherapy are often observed whether or not regimes with identical treatments were applied. Patient-related factors, the therapeutic process, and therefore the intrinsic factors of individual radiosensitivity are considered to b... see more

Introduction: Occupational exposure to ionizing radiation can potentially lead to adverse health effects, including cancer and genetic defects. Genetic damage caused by radiation can be detected if micronuclei are observed. The objective of this pilot stu... see more

This study aimed to determine the variables leukocytary, erythrocytary, frequency of micronuclei and nuclear abnormalities in peripheral erythrocytes of Prochilodus argenteus, Pimelodus maculates and Myleus micans from São Francisco river basin, Minas Ger... see more

Cytological biodosimetry methodology has been widely used for determining and estimating the precise irradiation dose received by victims in the situation of emergency irradiation exposure. The aim of this study was to assess the gamma-ray induced dicentr... see more

Industrial wastewater and agricultural practices are among the main activities discharging organic pollutants, such as Polychlorinated biphenyl (PCB) congeners and organochlorine insecticides (e.g. DDT - dichloro diphenyl trichloroethane), to the environm... see more

Although there are several publications that refer to the basic criteria established for the micronucleus (MN) test in exfoliated buccal cells, there is still a difference in the quantity, method of obtention and staining of the cells for the evaluation o... see more

Biological dosimetry based on cytogenetic markers such as dicentric chromosome (DC) and micronuclei (MN) is, until now, the most frequently used method to estimate the radiation dose in the radiological accident event. Another biomarker that recently gain... see more

Due to the increase in cardiovascular disease, it is urgent to research new effective and safe drugs and their combinations. Candesartan cilexetil, an angiotensin II receptor antagonist, is a precursor to the active form of candesartan. However, thes... see more

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