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23.085  Articles
1 of 2.309 pages  |  10  records  |  more records»
Events such as oxidative stress caused by spinal cord injury (SCI) are a serious condition because they negatively affect many organs. Alternative treatment options for this type of injury are quite limited. In this study, we planned to investigate the ef... see more

The need for careful therapeutic drug monitoring (TDM) arises for measurement of drugs with a narrow therapeutic index (NTIDs), as well as for assuring their safe and controlled replacement with generics. In particular, this category includes anti-epilept... see more

Background: The effect of valproic acid (VPA) monotherapy on thyroid function test is controversial. Objective: The aim of this study is to assess the effect of VPA monotherapy on thyroid function on short-term follow-up in children with newly diagnosed e... see more

The present research work is aimed to investigate the anti-oxidant/neuroprotective role of Resveratrol in reversing the valproic acid induced autism in postnatal swiss albino mice. Separate 13 day old/ Post natal day (PND) 13 swiss albino mice of either s... see more

Epigenetic events and genetic alterations under the control of the tumor microenvironment potentially mediate tumor induced angiogenesis involved in soft tissue sarcoma (STS) metastasis. Addition of antiangiogenic agent, such as bevacizumab, to standard c... see more

Erythropoietin (EPO) is a therapeutic protein that is widely used to increase red blood cell production in chronic kidney failure. EPO protein can be produced quickly with a transient gene expression system (TGE). However, the titer produced using TGE is ... see more

Purpose: To determine the effects of CYP3A5 polymorphisms on carbamazepine (CBZ) pharmacokinetic parameters when CBZ is used either as monotherapy or co-administered with phenytoin (PHT), phenobarbital (PB) or valproic acid (VPA). Methods: Retrospective d... see more

Neurotrophic factors play key roles in the development and survival of neurons. The potent neuroprotective effects of neurotrophic factors, including brain-derived neurotrophic factor (BDNF), ciliary neurotrophic factor (CNTF), glial cell-line derived neu... see more

Tingginya prevalensi penggunaan obat antiepilepsi pada pediatrik akan meningkatkan risiko timbulnya efek samping dan efek toksik, sehingga perlu adanya pemantauan kadar obat. Pemantauan kadar obat dapat dilakukan secara farmakokinetika dengan menghitung k... see more

1 of 2.309 pages  |  10  records  |  more records»