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448  Articles
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Hedgehog signaling pathway is physiologically activated during embryogenesis, especially in lung development. It is also reactivated in many solid tumors. In lung cancer, Hedgehog pathway is closely associated with cancer stem cells (CSCs). Recent works h... see more

Glioblastoma (GBM) remains an incurable disease, mainly due to the high migration and invasion potency of GBM cells inside the brain. PI3K/Akt, Sonic Hedgehog (SHH), and PKA pathways play major regulatory roles in the progression of GBM. The vasoactive in... see more

Olá, leitores do Boletim Dor On Line! Neste mês trazemos mais um editorial da série de quimiocinas, tratando neste mês da CCL2. Temos, também, alertas tratando do estudo da dor. Estes alertas foram apresentados no Congresso Científico Anual da Sociedade A... see more

Basal cell carcinoma (BCC) is the most common human malignancy, accounting for the majority of all non-melanoma skin cancers (NMSC). In the past several decades the worldwide incidence of BCC has constantly been increasing. Even though it is a slow growin... see more

O meduloblastoma é um tumor cerebelar caracterizado como tumor neuroectodérmico primitivo prevalente em crianças, sendo as do sexo masculinos as mais afetadas. Com relação à classificação histológica, existem cinco variações: clássico, desmoplásico, anapl... see more

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1 of 46 pages  |  10  records  |  more records»