Diseases  

Anna Angelousi, Dimitrios C. Ziogas, Vasiliki Siampanopoulou, Chrysoula Mytareli, Amalia Anastasopoulou, George Lyrarakis and Helen Gogas

Background: Checkpoint inhibitor (CPI)-associated diabetes mellitus (CPI-DM) is a rare immune-related adverse event (irAE) that presents with variable clinical manifestations. Data about its pathogenesis have not yet been adequately studied. Methods: Appl... see more

Kenji Yamagata, Satoshi Fukuzawa, Atsuro Noguchi, Shohei Takaoka, Fumihiko Uchida, Naomi Ishibashi-Kanno and Hiroki Bukawa

Neck control is a particularly important prognostic factor, and the diagnosis of neck metastasis at the initial examination is important for oral squamous cell carcinoma (OSCC). A pathologically negative neck does not guarantee future recurrence after pre... see more

Alexandrina Nastasa, Mohamad Hussam Sahloul, Corneliu Iorgulescu, ?tefan Bogdan, Alina Scarlatescu, Steliana Paja, Adelina Pupaza, Raluca Mitran, Viviana Gondos and Radu Gabriel Vata?escu

Background: Catheter ablation (CA) for atrial fibrillation (AF) is superior to antiarrhythmic drugs in maintaining sinus rhythm. Novel evidence suggests that increasing the time between the first diagnosis of AF and ablation, or diagnosis-to-ablation time... see more

Natalie Shi Qi Wong, Chang Liu, Molly Tzu-Yu Lin, Isabelle Xin Yu Lee, Louis Tong and Yu-Chi Liu

Introduction: This is a case report of a patient with neuropathic corneal pain after coronavirus disease 2019 (COVID-19) infection. Methods: A previously healthy 27-year-old female presented with bilateral eye pain accompanied by increased light sensitivi... see more

Koju Kamoi and Kyoko Ohno-Matsui

mRNA COVID-19 vaccines have been reported as protecting against COVID-19 and reducing its severity, and we have recognized post-vaccination symptoms recently. This research investigates the clinical trajectories of ocular disorders in a 51-year-old female... see more

Nelson Lu, Hooman Vaseli, Mobina Mahdavi, Fatemah Taheri Dezaki, Christina Luong, Darwin Yeung, Ken Gin, Michael Tsang, Parvathy Nair, John Jue, Marion Barnes, Delaram Behnami, Purang Abolmaesumi and Teresa S. M. Tsang

Background: Automated rhythm detection on echocardiography through artificial intelligence (AI) has yet to be fully realized. We propose an AI model trained to identify atrial fibrillation (AF) using apical 4-chamber (AP4) cines without requiring electroc... see more

Vladimira Durmanova, Miroslav Tedla, Dusan Rada, Helena Bandzuchova, Daniel Kuba, Magda Suchankova, Agata Ocenasova and Maria Bucova

HLA-G is the checkpoint molecule involved in the suppression of the immune response. Increased expression of HLA-G and its ILTs receptors have been correlated with tumor progression in various cancer types. In head and neck squamous cell carcinoma (HNSCC)... see more

Sonia Gentile, Liam R. Sullivan, Heather Brooks and Gordana Simeunovic

Patients receiving B-cell-depleting therapies (BCDT) are at an increased risk for severe COVID-19. Passive antibody therapy (PAT), including COVID-19 convalescent plasma (CCP) and monoclonal antibodies (mAb), may be an effective treatment in this populati... see more

Ebele C. Okoye, Amal K. Mitra, Terica Lomax and Cedric Nunaley

About half of the world’s population is at risk of dengue infection. Epidemics of dengue fever have caused an increased risk of morbidity and mortality in recent years, which led to the exploration of vaccines as a preventive measure. This systematic revi... see more

Saleh Ahmed, Shabiha Sultana, Shoumik Kundu, Sayeda Sadia Alam, Tareq Hossan and Md Asiful Islam

Zika virus (ZIKV) and chikungunya virus (CHIKV) are arthropod-borne viruses with significant pathogenicity, posing a substantial health and economic burden on a global scale. Moreover, ZIKV-CHIKV coinfection imposes additional therapeutic challenges as th... see more

Rumiko Shimizu, Nobuto Nakanishi, Manabu Ishihara, Jun Oto and Joji Kotani

Lean body mass is a significant component of survival from sepsis. Several equations can be used for calculating lean body mass based on age, sex, body weight, and height. We hypothesized that lean body mass is a better predictor of outcomes than the body... see more