Diseases  

Ravi Bharadwaj, Swati Jaiswal, Erandi E. Velarde de la Cruz and Ritesh P. Thakare

Solute carrier (SLC) transporters constitute a vast superfamily of transmembrane proteins tasked with regulating the transport of various substances such as metabolites, nutrients, ions, and drugs across cellular membranes. SLC transporters exhibit coordi... see more

Iyad Hassan, Lina Hassan, Farooq Bacha, Mohammad Al Salameh, Omran Gatee and Wiam Hassan

Background: Globally, the incidence of papillary thyroid cancer (PTC) has been increasing over the last few decades and it has become the second most common cancer in women in the UAE. There is some evidence to suggest that COVID-19 infection might be dir... see more

Catalin Vladut Ionut Feier, Calin Muntean, Sorana D. Bolboaca and Sorin Olariu

In light of the elevated incidence and consequential prognostic implications associated with colorectal cancer, a comprehensive investigation into the impact exerted by inflammatory status on patient management becomes imperative. A retrospective study sp... see more

Mei-Yun Cheng, Hsuan-Chen Ho, Jung-Lung Hsu, Yi Wang, Linyi Chen, Siew-Na Lim, Ming-Feng Liao and Long-Sun Ro

Various vaccines have been developed in response to the SARS-CoV-2 pandemic, and the safety of vaccines has become an important issue. COVID-19 vaccine-related central nervous system inflammatory demyelinating diseases (CNS IDDs) have been reported recent... see more

Victor Javier Cruz-Holguín, Luis Didier González-García, Manuel Adrián Velázquez-Cervantes, Haruki Arévalo-Romero, Luis Adrián De Jesús-González, Addy Cecilia Helguera-Repetto, Guadalupe León-Reyes, Ma. Isabel Salazar, Leticia Cedillo-Barrón and Moisés León-Juárez

In mammals, the placenta is a connection between a mother and a new developing organism. This tissue has a protective function against some microorganisms, transports nutrients, and exchanges gases and excretory substances between the mother and the fetus... see more

Elsa Vitale and Alessandro Rizzo

(1) Background: Several researchers have highlighted a higher incidence of overweight and obesity among nurses, and others have analyzed the quality of nurses’ eating habits and their related physical activity levels. The present study assessed the differ... see more

Ludovico Abenavoli

Vlad Barbos, Bogdan Feciche, Silviu Latcu, Alexei Croitor, Vlad Dema, Razvan Bardan, Flaviu Ionut Faur, Tudor Mateescu, Dorin Novacescu, Gherle Bogdan and Alin Adrian Cumpanas

This study presents a systematic review of the literature on individuals’ health-related quality of life (HRQoL) following radical cystectomy for muscle-invasive bladder cancer (MIBC), utilizing the Short Form-36 Health Survey (SF-36) as a primary assessm... see more

Amani A. Alrehaili, Amal F. Gharib, Maha M. Bakhuraysah, Afaf Alharthi, Ohud Alsalmi, Fouzeyyah Ali Alsaeedi, Reem Ali Alhakami, Kamilah Ali Alasmari, Nuha Mohammed and Wael H. Elsawy

Squamous cell carcinoma of the head and neck (HNSCC) is a globally prevalent form of cancer with significant morbidity and mortality rates. The present study examines the relationship of serum pro-inflammatory cytokines and leptin levels with the effectiv... see more

Leila Itani, Massimo Pellegrini, Dana Saadeddine, Hanen Samouda, Dima Kreidieh, Hana Tannir and Marwan El Ghoch

Slow gait speed is associated with poorer clinical outcomes and higher rates of functional limitation and mortality in older adults, especially when combined with overweight or obesity. Aging is also associated with nutritional deficits. The aim of our st... see more

Lehel-Barna Lakatos, Manuel Bolognese, Mareike Österreich, Laura Weichsel and Martin Müller

Objectives: Whether different antihypertensive drug classes in high blood pressure (HBP) pre-stroke treatment affect dynamic cerebral autoregulation (dCA), stroke severity, and outcome. Methods: Among 337 consecutive ischemic stroke patients (female 102; ... see more

Matteo Vassallo, Roxane Fabre, Laurene Lotte, Sabrina Manni and Christian Pradier

Introduction: Beta-lactamases are frequently prescribed for Gram-negative bloodstream infections (BSIs). However, chromosomally encoded AmpC-producing Enterobacterales (AE) could overproduce beta-lactamases when exposed to third-generation cephalosporins ... see more

Alexandra Papoudou-Bai, Epameinondas Koumpis, Georgia Karpathiou, Eleftheria Hatzimichael and Panagiotis Kanavaros

GATA3 is a transcription factor involved in T-cell maturation and has been previously shown to be aberrantly overexpressed in malignant Hodgkin and Reed–Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL). However, the immunophenotypes of the cell t... see more

John Dawi, Aishvaryaa Shree Mohan, Yura Misakyan, Scarlet Affa, Edgar Gonzalez, Karim Hajjar, David Nikoghosyan, Sabrina Fardeheb, Christopher Tuohino and Vishwanath Venketaraman

Meningitis is an inflammatory condition affecting the meninges surrounding the brain and spinal cord. Meningitis can be triggered by various factors, including infectious agents like viruses and bacteria and non-infectious contributors such as cancer or h... see more

Fajer M. AlKandari, Hussein S. Mohamed, Sayed A. Ahmed, Basant Mahmoud and Asmaa M. Mahmoud

Post-marketing hepatotoxicity findings are more common or occur much later. NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen are consumed in large quantities around the world. NSAIDs have a low incidence of hepatotoxicity but their wide use m... see more

Lucia Merlino, Agnese Immacolata Volpicelli, Franco Anglana, Giulia D’Ovidio, Mattia Dominoni, Marianna Francesca Pasquali, Barbara Gardella, Paolo Inghirami, Pietro Lippa and Roberto Senatori

Background: Hemangiomas are aberrant proliferations of blood vessels and the most frequent benign pediatric soft tissue tumors. Although they are common, genital localization is rare. This study aimed to assist doctors in the diagnosis, management, and tr... see more

Simona Laurino, Sabino Russi, Ludmila Carmen Omer, Alberto D’Angelo, Giovanni Bozza, Giuseppina Gallucci, Geppino Falco, Giandomenico Roviello and Anna Maria Bochicchio

The correlation between cancer and venous thromboembolism (VTE) is solid, whereas the knowledge about cancer-related arterial thromboembolism (ATE) still needs a deeper investigation to clarify its pathogenesis. We describe two cases that represent useful... see more

Mark Ayoub, Julton Tomanguillo, Carol Faris, Nadeem Anwar, Harleen Chela and Ebubekir Daglilar

Background: SARS-CoV-2 causes varied gastrointestinal symptoms. Cirrhosis patients face higher mortality rates from it, especially those with decompensated cirrhosis. This study examines SARS-CoV-2’s impact on decompensation in previously compensated cirr... see more

Rafael Fagundes Melo, Lucas Fornari Laurindo, Katia Portero Sloan, Lance Alan Sloan, Adriano Cressoni Araújo, Piero Bitelli, Tereza Laís Menegucci Zutin, Rodrigo Haber Mellen, Luciano Junqueira Mellen, Elen Landgraf Guiguer, João Paulo Cera Albarossi, Márcia Rocha Gabaldi, Patricia Cincotto dos S. Bueno, Jesselina Francisco dos Santos Haber, Sandra Maria Barbalho and Eduardo Federighi Baisi Chagas

The treatment of Type 1 Diabetes Mellitus (T1DM) has always been a challenge for health professionals in relation to glycemic control. Increased body fat has been related to a worsening of the lipid profile and increased prevalence of dyslipidemia in this... see more

Félix Úbeda, Sonia Santander and María José Luesma

Introduction: Hereditary fructose intolerance or hereditary fructosemia is an autosomal recessive metabolic disorder caused by a loss of function in the aldolase B gene. This disorder affects 1 in 20,000 people, constituting a rare disease with a favorabl... see more

Giuseppina Fanelli, Veronica Lelli, Sara Rinalducci and Anna Maria Timperio

The immune response to infectious diseases is directly influenced by metabolic activities. COVID-19 is a disease that affects the entire body and can significantly impact cellular metabolism. Recent studies have focused their analysis on the potential con... see more

Josip Lukenda and Josip Andelo Borovac

The impact of the COVID-19 pandemic on cardiovascular healthcare in Croatia remains largely unexplored. This study aimed to compare the utilization and provision of cardiovascular services during the pre-pandemic (2017–2019) and pandemic (2020–2021) perio... see more

Massimo Franchini, Daniele Focosi, Mario Cruciani, Michael J. Joyner, Liise-anne Pirofski, Jonathon W. Senefeld, Shmuel Shoham, David J. Sullivan and Arturo Casadevall

Plasma collected from people recovered from COVID-19 (COVID-19 convalescent plasma, CCP) was the first antibody-based therapy employed to fight the pandemic. CCP was, however, often employed in combination with other drugs, such as the antiviral remdesivi... see more