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29.546  Articles
1 of 2.956 pages  |  10  records  |  more records»
In this paper details about the results of a code-to-code validation procedure of an in-house developed building simulation model, called DETECt, are reported. The tool was developed for research purposes in order to carry out dynamic building energy perf... see more

Aim. This work aimed to validate an assay procedure for desloratadine tablets by direct spectrophotometric method.Materials and methods. A pilot-scale batch of the pharmaceutical preparation Alerdez, film-coated tablets containing 5 mg of desloratadi... see more

Topicality. Proof of bioequivalence of generic and reference drugs according to biovaser procedure based on the BCS for simplified registration provides for determination of solubility of active substance for establishing the BCS class and kinetics of its... see more

Efavirenz is a non-nucleoside reverse transcriptase inhibitor with a number of side effects manifested by psychiatric symptoms. There are cases of acute poisoning due to administration of efavirenz, including cases of suicide attempts; therefore, efaviren... see more

Doxylamine is a hypnotic medicine used for treatment of minor sleep disorders and is a frequent cause of poisoning.Aim. To develop GLC/MS-procedure of doxylamine quantification and carry out step-by-step validation ofthe developed procedure in the va... see more

Metronidazole belongs to the group of antiprotozoal medicines and widely used for the treatment of infectious diseases; the medicine has a number of side effects manifested by usual symptoms of acute intoxication, especially when interacting with other dr... see more

Isosorbide dinitrate is a universally recognized drug for the relief of angina attacks. Today, prolonged forms of isosorbide dinitrate are of great interest due to their high antianginal efficacy and lower frequency of side effects that are characteristic... see more

Aim. To develop and validate the new enzymatic kinetic photometric procedure for analysis of dequalinium chloride based on application of enzymatic acetylcholine hydrolysis to determine the residual quantities of dequalinium chloride while monitoring the ... see more

Introduction. Bioanalytical methodology is the founder of research on bioequivalence and therapeutic drug monitoring, so the focus of the study of pharmacokinetics and bioequivalence should be given to the development and validation of bioanalytical metho... see more

1 of 2.956 pages  |  10  records  |  more records»