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194.908  Articles
1 of 19.492 pages  |  10  records  |  more records»
Topicality. Proof of bioequivalence of generic and reference drugs according to biovaser procedure based on the BCS for simplified registration provides for determination of solubility of active substance for establishing the BCS class and kinetics of its... see more

Topicality. Proof of bioequivalence of generic and reference drugs according to biovaser procedure based on the BCS for simplified registration provides for determination of solubility of active substance for establishing the BCS class and kinetics of its... see more

Chemical, pharmacokinetic, and pharmacodynamics properties are available in the package inserts of every Food and Drug Administration (FDA) approved prescription drug, including all available chemotherapy drugs. These inserts follow a specific format impo... see more

A novel general approach was described to address many of the challenges of salt solubility determination of drug substances, with data processing and refinement of equilibrium constants encoded in the computer program pDISOL-XTM. The new approach wa... see more

The article presents an innovative approach to a bactericidal drug design based on a cephem prodrug analogue – cefetamet pivoxil hydrochloride. The emergence of cefetamet pivoxil hydrochloride excipient systems (mannitol, hydroxypropyl methyl cellulose, p... see more

Monomeric and polymeric phenolic derivatives have attracted renewed attention due to novel discoveries and applications in the pharmaceutical and food industries. Although lower and higher plants generally synthesize these compounds as allomones, antioxid... see more

Since there are conflicting reports in the literature on solubility and dissolution advantages of cocrystals over free forms, we systematically studied solubility and intrinsic dissolution rates of a weakly basic drug, ketoconazole, and its cocrystals wit... see more

The WHO Biopharmaceutical Classification System (BCS) is a practical tool to identify active pharmaceutical ingredients (APIs) that scientifically qualify for a waiver of in vivo bioequivalence studies. The focus of this study was to engage a global netwo... see more

Gamavuton-0 (GVT-0) is a new pharmaceutical  compound  that  has  proven  to  treat  the inflammatory disease at the joint and cartilage tissue. The study of effect of pH towards the solubility of GVT-0 is  importan... see more

1 of 19.492 pages  |  10  records  |  more records»