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9.284  Articles
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There were many diseases caused by viruses or bacteria. the virus or bacteria can mutate so that they could result the new disease. Sequence alignment was important so that it could be used to research genetic diseases and epidemics. In this reseach, we t... see more

Bioinformatics is a science that studies the management and analysis of biological information. Bioinformatics includes application of mathematics, statistics, and informatics to biological problems to solve. Bioinformatics can store data generated by the... see more

Bioinformatics computing is a kind of big data processing problem, which usually has the characteristics of large data scale, large computational load and long computational time. Therefore, the use of big data technology in bioinformatics computing has g... see more

Multiple Sequence Alignment (MSA) is one of the main topics in the bioinformatics domain, consists in ?nding an optimal alignment for three or more biological sequences with the number maximum of conserved zones or totally aligned columns. Different score... see more

BACKGROUND Nucleocapsid (N) protein is one of four structural proteins of SARS-CoV-2  which is known to be more conserved than spike protein and is highly immunogenic. This study aimed to analyze the variation of the SARS-CoV-2 N protein sequences in... see more

Sequence alignment is a necessarily step before analysing the phylogenetic relationships between organisms. The effect of the alignment method on the phylogenetic results has not been well studied. In Geneious software, the alignment can be performed usin... see more

Homology modelling is one of the important alternative techniques to X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy in structural determination of protein. CYP2D6 drug metabolizing enzymes have extensively studied prior to the suc... see more

In this paper, we introduce an improved parallel algorithm for computing the number of exact matches nid (S,T) in the local alignment of two biological sequences S and T. This number is used in the first stage of progressive alignment to compute the dista... see more

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