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25  Articles
1 of 3 pages  |  10  records  |  more records»
Homology modelling is one of the important alternative techniques to X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy in structural determination of protein. CYP2D6 drug metabolizing enzymes have extensively studied prior to the suc... see more

Objetivo: Investigar uma possível associação do gene CYP2D6 1846 G/A em pacientes que possuem AVEH/Aneurisma, residentes no Distrito Federal (Brasil) além de cruzar as informações obtidas com as manifestações clinicas e o prognóstico. Método: Tratou-se de... see more

Objetivo: Investigar uma possível associação do gene CYP2D6 1846 G/A em pacientes que possuem AVEH/Aneurisma, residentes no Distrito Federal (Brasil) além de cruzar as informações obtidas com as manifestações clinicas e o prognóstico. Método: Tratou-se de... see more

Literatures about case-control study on the association between CYP2D6*10 gene polymorphism and breast cancer were searched from last updated on May, 2014. Odds ratio of CYP2D6*10 gene distributions in breast cancer patients against healthy control were a... see more

Drug therapeutic efficiency and development of unfavorable pharmacologic responses as well as the disease predisposition are caused first of all by patient’s genetic features. Genetic variations in genes encoding drug-metabolizing enzymes and transporter ... see more

Drug therapeutic efficiency and development of unfavorable pharmacologic responses as well as the disease predisposition are caused first of all by patient’s genetic features. Genetic variations in genes encoding drug-metabolizing enzymes and transporter ... see more

This study was aimed to understand differences of ondansetron serum concentrationin each antiemetic responses, polymorphisms of 5HT3B receptor, CYP2D6 and ABCB1genes in Indonesian cancer patients treated with high emetogenic cytostatics. We recruitedcance... see more

PURPOSE: The inhibitory effects of antidepressants, such as imipramine, desipramine, and fluvoxamine, on dopamine formation from p-tyramine catalyzed by cytochrome P450 (CYP) 2D6.2 (Arg296Cys, Ser486Thr) and CYP2D6.10 (Pro34Ser, Ser486Thr), were compared ... see more


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