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8.085  Articles
1 of 809 pages  |  10  records  |  more records»
Introduction: The primary objective of this study was to evaluate the baseline characteristics of Lynch syndrome (LS). Furthermore, the study aimed to evaluate overall survival (OS) among patients with LS. Materials and Methods: This was a retrospective s... see more

Introduction: About 5% of endometrial cancer cases can be genetic and inherited. Lynch syndrome, also called hereditary non-polyposis colorectal cancer (HNPCC), is an autosomal dominant syndrome. Caused by a germline mutation in one of the DNA mismatch re... see more

Colorectal cancers with high frequency microsatellite instability (MSI-H) account for 15-20% of all colorectal cancers (CRC).  The familial form of MSI-H CRC is Lynch syndrome, caused by germline mutation in mismatch repair (MMR) genes, accounting fo... see more

A 40-year-old Caucasian male presented to the Emergency Department complaining of intermittent painless frank haematuria. Past medical history was significant for Hereditary Non-Polyposis Colon Cancer (HNPCC) and a prophylactic total colectomy. Computed t... see more

RÉSUMÉObjectif. le but du présent travail est d’illustrer l’intérêt de l’immunohistochimie (IHC) dans la recherche étiologique des cancers colorectaux (CCR) héréditaires. Patients et Méthodes. Par la technique d’IHC, nous avons analysé 34 CCR familiaux su... see more

Colorectal cancer is one of the most common cancer worldwide. The incidence and mortality trend in different areas of the world varies. Colorectal cancer incidence and mortality are increasing in some countries. There are also epidemiological shift toward... see more

Background: Colorectal cancer (CRC) is the second most common cancer worldwide. Estimated lifetime risk of CRC is 5%, with an incidence of 1 million new cases and 600?000 deaths worldwideevery year. Lifestyle, dietary, and genetic factors play a crucial p... see more

Introduction: Constitutional mismatch repair deficiency (CMMRD) is a rare autosomal recessive disease-carrying an increased risk of cancers (pediatric tumors of central nervous system, haemato-lymphoid malignancies along with gastrointestinal (GI) cancer(... see more

Objective: To evaluate the efficacy of PPH management by conservative surgical management using B-Lynch Method and Surabaya method (Modified B-Lynch compression suture) as an alternative to hysterectomy in PPH due to uterine atony.Method: Eighty-four case... see more

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