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17  Articles
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Colorectal carcinogenesis induced by cigarette smoke requires at least 30-40 years. This long time duration causes an animal research conducted becomes relevant. This research was carried out to observe colorectal carcinogenesis due to cigarette smoke exp... see more

Memoria del VII Simposio Nacional de Ciencias Farmacéuticas y Biomedicina y el V Simposio Nacional de Microbiología Aplicada 2020, edición virtual

BACKGROUND Hereditary nonpolyposis colorectal cancer, or Lynch syndrome, caused by germline mutations or genetic defects in mismatch repair (MMR) genes (MLH1, MSH2, PMS2, MSH6, and epithelial cellular adhesion molecule), is an autosomal dominant condition... see more

BACKGROUND: Colorectal cancer (CRC) is one of the most common cancers worldwide. Microsatellite instability (MSI) is detected in about 15% of all colorectal cancers. CRC with MSI has particular characteristics such as improved survival rates and better pr... see more

Introduction: The primary objective of this study was to evaluate the baseline characteristics of Lynch syndrome (LS). Furthermore, the study aimed to evaluate overall survival (OS) among patients with LS. Materials and Methods: This was a retrospective s... see more

 
Colorectal Cancer (CRC) is the third most commonly diagnosed cancer with over 1.9 million new cases worldwide in 2020. Accurate patient classification is imperative for the identification of the group of patients likely responding to treatment while conse... see more

Introduction: Constitutional mismatch repair deficiency (CMMRD) is a rare autosomal recessive disease-carrying an increased risk of cancers (pediatric tumors of central nervous system, haemato-lymphoid malignancies along with gastrointestinal (GI) cancer(... see more

Introducción y objetivos: la vía de inestabilidad de microsatélites (IMS) está implicada en la carcinogénesisde un 15 % de carcinomas colorrectales (CCR). La detección de esta alteración tiene relevancia en elpronóstico y en el tratamiento de los paciente... see more


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