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296.305  Articles
1 of 29.631 pages  |  10  records  |  more records»
A structure-based lead optimization procedure is an essential step to finding appropriate ligand molecules binding to a target protein structure in order to identify drug candidates. This procedure takes a known structure of a protein-ligand complex as in... see more

Leukemia drug discovery based on calanone compound was conducted in previous research and produced 6 calanone derivatives. Most of them have lower activities against leukemia cell L1210 than pure calanone. A Quantitative Structure-Activity Relationship (Q... see more

The purpose of designing a drug inventory accounting information system is to speed up the delivery of drug availability information and make it easier to search for effective and efficient drug data. The author uses data collection techniques by means of... see more

The interest in using physiologically-based pharmacokinetic (PBPK) models as a support to the drug development decision making process has rapidly increased in the last years. These kind of models are examples of the “bottom up” modelling strategy, which ... see more

Graphene-based nanomaterials have exhibited wide applications in nanotechnology, materials science, analytical science, and biomedical engineering due to their unique physical and chemical properties. In particular, graphene has been an excellent nanocarr... see more

Fragment-based drug design (FBDD) is one of the modern techniques used for developing new drugs, and an alternative to the widely used high throughput screening. The main methodological approaches of FBDD, as well as the methods of optimization for the id... see more

Shear walls' placement in specific positions could develop different structural responses to the building and affect the structure's strength to the received lateral loads. This research aims to find the variations in the shear walls' placement on the str... see more

Shear walls' placement in specific positions could develop different structural responses to the building and affect the structure's strength to the received lateral loads. This research aims to find the variations in the shear walls' placement on the str... see more

1 of 29.631 pages  |  10  records  |  more records»