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67  Articles
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In recent years, a significant success has been achieved in the treatment of breast cancer with the development of new effective therapeutic regimens in addition to traditional therapies. Along with the mentioned positive trends an increasingly urgent pro... see more

With the development of human's modern society more and more people tend to use complementary and alternative medicine (CAM). Toxicological studies indicated that many herbal medicines have direct toxic effects on the circulatory system or cardiovascular ... see more

Trastuzumab, a humanized monoclonal antibody against the extracellular domain of human epidermal growth factor receptor 2 (HER-2) prolongs disease-free survival (DFS) and overall survival (OS) in patients with early-stage breast cancer. Although it is gen... see more

Oxidative stress is a determining factor in the pathophysiology of heart disease. This study aimed at evaluating the protective activity of Abengourou Forastero cocoa in doxorubicin-induced cardiotoxicity in rats. Thirty (30)  wistar rats divided int... see more

The limitation of echocardiography to measure chemotherapy cardiotoxicity at left locally advanced breast cancer with large ulcer is still serious problem. HsTnI and erCRP are biomarkers to detect cardiotoxicity that are cheap, easy to examine and availab... see more

Chemotherapy with cyclophosphamide, adriamycin, and fluorouracil (CAF) regiment in patients with locally advanced breast cancer have a risk of cardiotoxicity. Cardiotoxicity examination standards using left ventricular ejection fraction (LVEF) by echocard... see more

Currently, a common therapeutic approach in cancer treatment encompasses a drug combination to attain an overall better efficacy. Unfortunately, it leads to a higher incidence of severe side effects, namely cardiotoxicity. This work aimed to assess the cy... see more

Sodium nitroprusside (SNP) is used clinically as a rapid-acting vasodilator and in experimental models as donor of nitric oxide (NO). High concentrations of NO have been reported to induce cardiotoxic effects including apoptosis by the formation of reacti... see more

Cardiotoxicity is a condition where damages caused by toxic chemical exposure are observed in heart and blood vessels. Doxorubicin is the most common chemotherapy agents for various types of cancer therapy. However, doxorubicin is converted into doxorubic... see more

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