24 articles in this issue
Bastiana Bastiana,Muzaijadah Retno Arimbi
Tuberculosis (TB) remains a major health problem worldwide. The bacteriological diagnosis of TB is confirmed by a sputum smear, which shows a positive result. Sputum culture conversion at two months of TB therapy has a higher possibility of completing the... see more
Muthia Maraya Hasna,Sri Widyaningsih,M. Reza Utama,Gina Noor Djalilah
Sepsis can occur in patients with Systemic Inflammatory Response Syndrome (SIRS) symptoms, especially in neonates due to their underdeveloped immune systems. Blood culture as the gold standard test to diagnose sepsis in SIRS patients takes a long time to ... see more
Ravell Hansen Untono,Jusak Nugraha,I. Gde Rurus Suryawan,Andrianto Andrianto
Coronary heart disease is a highly frequent illness in both developed and developing nations. Non-HDL cholesterol (n-HDL-c) and LDL cholesterol (LDL-c) stages are biomarkers that doctors frequently utilize to assess the risk of Coronary Heart Disease (CHD... see more
Ahmad Mulyadi Sunarya,MI. Diah Pramudianti,Yuwono Hadisuparto
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease with various complications, including osteoporosis. However, Bone Mineral Density (BMD) examination, a gold standard for diagnosing and monitoring osteoporosis, is static. Alk... see more
Eirene Jaquelene Tomatala,Anton Sumarpo,Hani Susanti
Locally established clinical laboratory reference value are required to interpret laboratory test results for screening, diagnosis, prognosis, determining retest criteria or as microscopic confirmation. The objective of this study is to establish urine se... see more
Hesty Rhauda Ashan,Husni Husni,Eugeny Alia
Sepsis is a medical emergency that describes systemic inflammation reaction to infectious process that can lead to organ dysfunction and death. Sequential Organ Failure Assesment (SOFA) score is used to assess severity of organ dysfunction in septic patie... see more
Pusparini Pusparini,Alvina Alvina
An automatic hematology analyzer is an essential instrument for the modern laboratory. A new hematology analyzer must undergo comparability testing with a currently used hematology analyzer. This study aimed to compare the performance of the Dymind DH-76 ... see more
Phey Liana,Norlaila Binti Chahril,Sri Nita,Tungki Pratama Umar
Production of Extended-Spectrum Beta-Lactamase (ESBL) by Enterobacteriaceae continues to be a problem of infectious diseases, especially in hospitals. The main causes of ESBL-producing bacteria colonization are urinary tract infections, length of hospital... see more
Rahmania Chandra Savitri,Dian Ariningrum,Yusuf Ari Mashuri
Urinary Tract Infections (UTIs) are among the most common bacterial infections in the community, including infants and children. Urine culture is the gold standard test for UTI detection, but it is expensive, impractical and takes a long time. At present,... see more
Raissa Yolanda,Delita Prihatni,Coriejati Rita,Dewi Kartika Turbawaty
Hemophilia A is an inherited factor VIII deficiency disease, related to X chromosome. Diagnosis of Hemophilia A is made based on Factor VIII assay. Nowadays, Hemophilia A therapy is by giving factor VIII concentrate, so that monitoring of this therapy mus... see more
Fachrurrodji Fachrurrodji,B. Rina A. Sidharta,Dian Ariningrum,JB. Suparyatmo,MI. Diah Pramudianti
Community-Acquired Pneumonia (CAP) is the most common cause of death and illness in the world. Increased IL-6 can be used as an early indicator of infection or inflammation. Ginseng is a popular herbal medicine. The anti-inflammatory effect of Ginseng is ... see more
Shofia Widya Murti,Delita Prihatni,Adhi Kristianto Sugianli
Coronavirus Disease-19 (COVID-19) is caused by Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2). In severe cases, the immune response may cause a cytokine storm. Neutrophil Lymphocyte Ratio (NLR) and D-dimer are parameters that may be used to... see more
Surawijaya Bakhtiar Kaslam,Umi Solekhah Intansari
Systemic Lupus Erythematosus (SLE) is an autoimmune disease that affects various body organs and causes chronic inflammation. Thrombocytopenia is common in SLE, and there is a risk of causing bleeding, which can result in death. This study aimed to analyz... see more
Ullifannuri Rachmi,Rima Yuliati Muin,Suci Aprianti,Liong Boy Kurniawan
Management of acute ischemic stroke patients based on their severity in emergency services is critical. One of the easy, fast, and affordable biochemical markers is serum sodium and albumin, which correlate with the severity of acute ischemic stroke. This... see more
Agustin Iskandar,Aditya Sri Listyoko,Hambiah Hari Oki
COVID-19 is a disease caused by SARS-CoV-2. Haematology alterations like lymphopenia is common, but not much study involves about thrombocyte. Incidence of thrombocytopenia in COVID-19 patient is 5-53.6%. Purpose of this study is to analyze diagnostic val... see more
Luhung Budiailmiawan,Ryan Bayusantika Ristandi,Azzania Fibriani
The standard molecular technique to detect the SARS-CoV-2 virus is The Real-Time Reverse-Transcription Polymerase Chain Reaction (rRT-PCR). It requires sophisticated equipment and a time-consuming sample process. The Cross Priming Amplification (CPA) is a... see more
Tigor Pandapotan Sianturi,Puspa Wardhani,I Dewa Gede Ugrasena
Infection is a significant cause of morbidity and mortality in childhood malignancy with Febrile Neutropenia (FN). Tumor Necrosis Factor-Alpha (TNF-a) is involved in host defense against bacterial invasion. However, changes in TNF-a levels with the possib... see more
Dias Setiawan,B. Rina A. Sidharta,Dian Ariningrum
Hematuria is a sign of glomerular and non-glomerular kidney disease. Erythrocytes that pass through the glomerulus will change shape to become dysmorphic. Dysmorphic red blood cells (dRBC) can be screened using an automatic urine analyzer based on flowcyt... see more
Maimun Zulhaidah Arthamin
Sepsis leads to local and systemic activation of different response systems, including coagulation and fibrinolysis. An overwhelming inflammatory response may lead to organ failure, and the coagulation and fibrinolysis involvement may lead to Disseminated... see more
Betti Bettavia Hartama Pardosi,Sianny Herawati,Ni Kadek Mulyantari
Down Syndrome (DS) is one of the common chromosomal disorders that raise mental retardation. It is known that DS patients have an autoimmune disorder affecting the endocrine and non-endocrine organs. It is a rare occurrence of type 2 Diabetes Mellitus (ty... see more
Putu Yudi Adnyani,I Nyoman Wande,Sianny Herawati
Pancreatitis is inflammation of the pancreatic parenchyma and diagnosed based on symptoms of heartburn accompanied by increased levels of pancreatic enzymes. Acute pancreatitis in acute lymphoblastic leukemia in addition to being caused by therapy can als... see more