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38.646  Articles
1 of 3.866 pages  |  10  records  |  more records»
Huntington disease (HD) is a progressive neurodegenerative disorder, characterized by autosomal dominant inheritance, movement disorder, dementia, and behavioural disturbances. It is caused by a mutation in IT15 gene on chromosome 4p16.3, which leads to u... see more

Due to the complexity of the pathological mechanisms of neurodegenerative diseases, traditional differentially-expressed gene selection methods cannot detect disease-associated genes accurately. Recent studies have shown that consensus-guided unsupervised... see more

Introduction: Huntington’s disease (HD) is an inherited neurodegenerative disease which affects the movement and leads to the progressive cognitive deficits and behavioral capacities. Care for a Huntington patient is a complex process with a major impact ... see more

Neurodegenerative diseases are incurable and devastating neurological disorders characterized by the progressive loss of the structure and function of neurons in the central nervous system or peripheral nervous system. Mitochondria, organelles found in mo... see more

AbstractThe Hooper Visual Organization Test (HVOT) was designed to measure an individual’s ability to organise visual stimuli and assess visual-spatial abilities and synthesis. The current investigation sought to explore the psychometric properties of the... see more

Neurodegenerative disease is a range of conditions which primarily affect the neurons in the human brain. Neurons are the building blocks of the nervous system which includes the brain and spinal cord. Neurodegenerative diseases are incurable and debilita... see more

Huntington’s disease (HD) is a hereditary neurological disorder with a late onset and a long period of progression that is characterized by changes in personality and physical aptitude. Predictive testing for HD was introduced in 1993 but there have been ... see more

Huntington’s disease is a progressive, degenerative disease characterized by abnormal body movements symptoms like chorea and a reduction of body weight . Recently, it has been reported that oxidative stress, which is one of the pathological hallmarks of ... see more

Stem cells in the adult brain subventricular zone (SVZ) generate new neurons that migrate to the olfactory bulb. About half of the new neurons survive and become functional interneurons. SVZ stem cells are being studied to discover if there are ways to en... see more

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