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48.790  Articles
1 of 4.879 pages  |  10  records  |  more records»
The strategy of rational approaches to the search for selective COX-2 inhibitors as potential antiinflammatory agents has been proposed and elaborated. It is based on the use of PASS-prediction and molecular docking. The choice of the basic structure of 4... see more

An effective method for synthesis of 6-(1H-benzimidazol-2-yl)-5-methylthieno[2,3-d]pyrimidine-4(3H)-thione starting from the corresponding 4-oxo analog has been developed. For the chemical diversity enlargement the alkylation of 6-(1H-benzimidazol-2-yl)-5... see more

The strategy of rational approaches to the search for selective COX-2 inhibitors as potential antiinflammatory agents has been proposed and elaborated. It is based on the use of PASS-prediction and molecular docking. The choice of the basic structure of 4... see more

An effective method for synthesis of 6-(1H-benzimidazol-2-yl)-5-methylthieno[2,3-d]pyrimidine-4(3H)-thione starting from the corresponding 4-oxo analog has been developed. For the chemical diversity enlargement the alkylation of 6-(1H-benzimidazol-2-yl)-5... see more

The leaf katuk (Sauropus androgynus L. Merr) extract at a dose of 400 mg / kg BW had antiinflammatory activity in rat by induction of carrageenan. Patch are adhesive plasters containing medicinal substances placed on the skin to delivery active substances... see more

For the first time the possibility of intensifying the grinding process of pure sulfur (a substance of 33% sulfur ointment) with the use of surfactant – sodium lauryl sulfate (LS-Na); gelatosa and their mixture was shown. The dispersing activity of surfac... see more

Background: Glutathion S-transferase (GST) is a group of multifunction isoenzymes playing a role as katalisator in releasing inflammatory mediators prostaglandin and leukotrien. Non-steroidal antiinflammatory drugs (NSAID) such as pentagamavunon-0 (Pgv-0)... see more

BACKGROUND: Vitamin D has a role in downregulating the proinflammatory cytokines as well as promoting the antiinflammatory pathway in rheumatoid arthritis (RA). Seluang fish (Rasbora sp.) has potency as a new source of vitamin D. Previous study had proven... see more

1 of 4.879 pages  |  10  records  |  more records»