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Volume 21 Number 2 Year 2023

21 articles in this issue 

Andri Prasetiyo, Wiwi Winarti, Rini Agustia

People have long utilised the leaves of the red gedi, Abelmoschus manihot (L.) Medik is an anti-diabetic medication. The study’s objectives were to classify chemical constituent groups, assess extract quality, and evaluate the activity of a-glucosidase en... see more

Pags. 159 - 164  

Manuel Hutapea, Greesty Finotory Swandiny, M. Irfan Syafawi, Fahreza Pratama Putra, Sucipto Kokadir, Edward Basilianus, Vinessa Gracia Putri, Syamsudin Abdillah

Sea cucumbers are deep-sea-dwelling invertebrate animals that are rich in nutrients and have been empirically used to prevent various degenerative diseases, especially due to their ability to dampen free radicals. The purpose of this study was to identify... see more

Pags. 165 - 171  

Putu Rika Veryanti, Ratu Ayu Dewi Sartika, Rani Sauriasari, Berna Elya, Rara Merinda Puspitasari

Community activity restrictions during the COVID-19 pandemic in Indonesia impact the quantity and quality of health services for type 2 diabetes (T2DM). This limitation could increase the risk of hypoglycemia in type 2 diabetes patients. The study aimed t... see more

Pags. 172 - 178  

Devi Nurhasana, Rahmaga Febriansyah, Avidlyandi Avidlyandi, Salprima Yudha S., Charles Banon, Dwita Oktiarni, Morina Adfa

The purpose of this study was to look into the antibacterial activity of methanolic extract of Excoecaria cochinchinensis as well as the effect of its combination with antibiotics on the growth of Klebsiella pneumoniae, Enterobacter aerogenes, and Staphyl... see more

Pags. 179 - 185  

Junvidya Heroweti, Danang Novianto Wibowo, Himatul Khoeriyah, Ramadhania Adelia

Cinnamaldehyde in cinnamon essential oil, lauric acid, myristic acid, and oleic acid in virgin coconut oil (VCO) were used in hair tonic preparations as hair growth agents. This study aimed to evaluate particle size and obtain optimum formulation of the h... see more

Pags. 186 - 192  

Nurita Andayani, Raise Maninda, Rosa Marlina, Qoina Noviantani, Khaled Qalalwa

Mycobacterium tuberculosis causes Tuberculosis (TB), an infectious disease. The study aims to evaluate DOTS therapy's impact on pulmonary TB and TB-HIV patients. This research used a descriptive qualitative study design with a retrospective descriptive re... see more

Pags. 193 - 200  

Inta Nurhaliza, Galar Sigit Prasuma, Ergia Andang Sugiantoro, Lianawati Lianawati, Praewthip Sutheeraprasert, Didik Setiawan

Dyspepsia is a common digestive disorder among global health problems. This study aimed to examine the cost-effectiveness of scientific herbs in the treatment of dyspepsia. This study has used a societal perspective, but the indirect costs are considered ... see more

Pags. 201 - 208  

Faizatun Faizatun, Irene Intan Permata Murti

Mulberry is a plant that has been shown to be effective as a whitening agent. The objective of this research was to evaluate the efficacy of mulberry root extract (MRE) and its nanostructured lipid carrier (NLC) extracts in terms of their ability to light... see more

Pags. 209 - 214  

I Gusti Agung Ayu Kartika, Suryani Suryani, Dwi Hadi Setya Palupi, I Ketut Adnyana

Sirih bumi (Peperomia pellucida [L.] Kunth.) is a medicinal herb. Anti-inflammatory activities are reported. These plant extracts have been shown to reduce inflammation in many studies, but it is unknown which extract works best. The objectives if this st... see more

Pags. 215 - 222  

Desi Nadya Aulena, Dwi Fitri Yani, Mariyamah Mariyamah, Muhammad Lufika Tondi, Muhammad Dandi, Hafis Kiki Wahyudin, Dany Raihan

The SARS-CoV-2 virus is the infectious agent that causes COVID-19, a feverish condition brought on by inflammation in the infected patient’s body. Sungkai leaf (Peronema canescens Jack) is one of the Indonesian people who rely on herbal remedies to treat ... see more

Pags. 223 - 230  

Tias Eka Rahmawati, Agus Siswanto, Asmiyenti Djaliasrin Djalil

Diphenhydramine HCl is an antihistamine drug that is available in conventional tablet form. This study aimed to produce the optimum formula for a diphenhydramine fast disintegrating tablet (FDT) using a modification of starch, crospovidone, and microcryst... see more

Pags. 231 - 238  

Nina Salamah, Arum Fatmawati, Any Guntarti

Gelatin is widely used in the food industry, including soft candy. It is generally sourced from cows and pigs. However, adding porcine gelatin to food will be problematic for the Muslim community due to its prohibition in their beliefs. Therefore, the sof... see more

Pags. 239 - 246  

Muhammad Alfian, Nining Sugihartini, Sapto Yuliani

This research aimed to evaluate how enhancers affect the properties of Syzygium aromaticum oil in both water-soluble and hydrocarbon bases. Physical and chemical characteristic tests, irritation index evaluations, and anti-inflammatory activity assessment... see more

Pags. 247 - 253  

Nisa Maria, Ferlina Vidyananda Susilo, Mayannaria Simarmata

Antihypertensive and antidiabetic drugs in CKD patients on hemodialysis may cause medication-related problems requiring monitoring. This study aimed to evaluate the selection, dosage, and potential drug interactions of antihypertensive and antidiabetic dr... see more

Pags. 254 - 265  

Lili Musnelina, Fitri Handayani, Thanh - Hoa Vo, Jenny Pontoan

Treatments used in atrial fibrillation therapy, such as those of anticoagulants, consist of vitamin K antagonists (warfarin) and direct oral anticoagulants (dabigatran, apixaban, rivaroxaban, and edoxaban). The use of warfarin requires regular monitoring ... see more

Pags. 266 - 272  

Rika Sari Dewi, Ni Made Dwi Sandhiutami, Beatrix Melani Evangelia, Muhammad Taher Bakhtiar

Cinnamon bark is known as a medicinal plant to has anti-inflammatory and analgesic effects in vitro. This activity is due to bark of cinnamon containing several compounds including cinnamaldehyde, cinnamic alcohol, cinnamic acid and coumarin. The aim of t... see more

Pags. 273 - 278  

Aguslina Kirtishanti, Devyani Diah Wulansari, Dini Kesuma, I Gusti Ayu Laksmi Dwi Putri, Amirah Nabila Rahmadinar

Tribulus terrestris and Panax ginseng are two therapeutic plants that might increase libido. The aim of the study was to see the effects of herbal medicine containing Tribulus terrestris and Panax ginseng on increasing male mice libido. This study used mi... see more

Pags. 279 - 285  

Safira Nafisa, Siti Umrah Noor, Azkannufuus Azkannufuus, Yuslia Noviani

Kenikir leaves (Cosmos caudatus Kunth.) contain quercetin, which has anticancer properties. To provide more effective complementary therapy for breast cancer, nanotechnology was applied to develop preparations containing kenikir leaf extract. This researc... see more

Pags. 286 - 294  

Kartika Citra Dewi Permata Sari, Nisa Maria, Larasati Arrum Kusumawardani, Hindun Wilda Risni, Nadia Farhanah Syafhan, Afina Nur Fauziyyah

Antihypertensive and antidiabetic drugs in chronic kidney disease (CKD) patients undergoing hemodialyThe high demand for telepharmacy services led to the urge for proper training and education to enhance its quality. This review aimed to assess the implem... see more

Pags. 295 - 302  

Sondang Khairani, Hesty Utami Ramadaniati, Prih Sarnianto, Erna Kristin, Yusi Anggriani

AbstractOveruse of antibiotics is a public health challenge that can lead to antimicrobial resistance. To reduce the occurrence of antibiotic resistance, it is necessary to evaluate the use of antibiotics to determine the rational use of drugs using quant... see more

Pags. 303 - 310