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197  Articles
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Chromatin structure at high levels of its organization, which remains not to be completely understood, attracts much attention because it is the basis of regulation of functional processes in nuclei of eukaryotic cells. An important aspect of this organiz... see more

Chromatin assembly factor-1 (CAF-1), a protein complex consisting of three subunits, p150, p60, and p48, is highly conserved from yeast to humans and facilitated nucleosome assembly of newly replicated DNA. The p48 subunit, CAF-1p48 (p48), with seven WD (... see more

Nucleosomes are considered dynamic particles that are involved in practically all chromosomal processes, being subjected to highly ordered changes considered as epigenetic information, which modulates DNA accessibility. Nucleosomes exhibit three dynamic p... see more

The regulation of cellular metabolism is coordinated through a tissue cross-talk by hormonal control. This leads to the establishment of specific transcriptional gene programs which adapt to environmental stimuli. On the other hand, recent advances sugges... see more

Eukaryotic DNA replication occurs in the context of chromatin. Recent years have seen major advances in our understanding of histone supply, histone recycling and nascent histone incorporation during replication. Furthermore, much is now known about the r... see more

Chromatin 3D structure is highly dynamic and associated with many biological processes, such as cell cycle progression, cellular differentiation, cell fate reprogramming, cancer development, cellular senescence, and aging. Recently, by using chromosome co... see more

Regulation of gene expression is achieved by sequence-specific transcriptional regulators, which convey the information that is contained in the sequence of DNA into RNA polymerase activity. This is achieved by the recruitment of transcriptional co-factor... see more

Stingless bees are important pollinators for various plant crops. We investigated the susceptibility of Tetragonisca fiebrigi to sublethal concentrations of insecticides fipronil, malathion, and thiamethoxam (administered through contact and ingestion) by... see more

Ultrastructural studies conducted in situ using conventional transmission electron microscopy have had relatively little impact on defining the structural organization of chromatin. This is due to the fact that in routine transmission electron microscopy,... see more

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