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2.425  Articles
1 of 243 pages  |  10  records  |  more records»
Whereas autism spectrum disorder (ASD) exhibits striking heterogeneity in genetics and clinical presentation, dysfunction of mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway has been identified as a molecular feature common to several ... see more

The annual meeting “Signal Transduction—Receptors, Mediators, and Genes” of the Signal Transduction Society (STS) is an interdisciplinary conference open to all scientists sharing the common interest in elucidating signaling pathways in ... see more

Failure of axon regeneration in the central nervous system (CNS) of mammals is due to both extrinsic inhibitory factors and to neuron-intrinsic factors. The importance of intrinsic factors is illustrated in the sea lamprey by the 18 pairs of large, indivi... see more

Silver nanoparticles (AgNPs), an emerging environmental contaminant, have been developed as antimicrobials, biosensors, and for other applications in products ranging from medical devices to consumer goods including toothpaste, socks, and appliances. AgNP... see more

Trimethyltin (TMT, 2.4mg/kg, i.p) can trigger neuronal damage by inhibiting Tropomyosin receptor kinase B (TrkB receptor) following by phosphoinositide 3-kinase (PI3K)/protein kinase B or Akt signaling cascade. We examined hippocampal changes in TrkA/B ph... see more

Costa, L., Giordano, G., & Guizzetti, M. (2013). Inhibition of cholinergic muscarinic signaling by ethanol: Potential mechanism of developmental neurotoxicity and biological plausibility for the beneficial effects of choline supplementation. The Internati... see more

Fetal Alcohol Spectrum Disorders (FASD) are associated with changes in proliferation and induced cell losses of neuronal stem cells during development.  Alcohol induced oxidative stress has been noted in previous studies to cause chronic genomic inst... see more

Costa, L., Giordano, G., & Guizzetti, M. (2013). Inhibition of cholinergic muscarinic signaling by ethanol: Potential mechanism of developmental neurotoxicity and biological plausibility for the beneficial effects of choline supplementation. The Internati... see more

Alcoholism initiates with episodes of excessive alcohol drinking, known as binge drinking, which is one form of excessive drinking (NIAAA Newsletter, 2004) that is related to impulsivity and anxiety (Ducci et al., 2007; Edenberg et al., 2004) and is also ... see more

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